Purpose: Purpose: a commonly recognized complication of intravitreal steroids is secondary ocular hypertension (OHT). The aim of this retrospective study is to further characterize the effects of sustained-release intravitreal dexamethasone implants (SIDIs) on intraocular pressure (IOP). Specifically, we describe time course, incidence, and pharmacological management of OHT in eyes receiving repeated injections. Methods: Methods: this study included 78 eyes (78 patients) and 154 SIDIs injections over 3 years. Mean age: 67±13.4 SD, 48 males (62%) and 30 females (38%). SIDIs contained 0.7 mg of dexamethasone. Goldmann tonometry was performed at baseline (T0, before the injection) and at 1 week (T1w), 1 month (T1m), 3 months (T3m), and 6 months (T6m) after each intravitreal injection (INJ). Statistical analysis was performed using the Friedman test. Inclusion criteria: macular edema secondary to retinal
Intraocular hypertension due to repeated injections of intravitreal dexamethasone for macular edema: a 3-year observational study / Pacella, F; Pacella, E; Taverniti, L; Battagliola, Et; Turchetti, P; Pannarale, L. - In: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. - ISSN 0146-0404. - 60:9(2019), pp. 3200-3200. ( ARVO 2019 Annual Meeting Vancouver, Canada, ).
Intraocular hypertension due to repeated injections of intravitreal dexamethasone for macular edema: a 3-year observational study
Pacella, FPrimo
;Pacella, ESecondo
;Taverniti, L;Turchetti, PPenultimo
;Pannarale, LUltimo
2019
Abstract
Purpose: Purpose: a commonly recognized complication of intravitreal steroids is secondary ocular hypertension (OHT). The aim of this retrospective study is to further characterize the effects of sustained-release intravitreal dexamethasone implants (SIDIs) on intraocular pressure (IOP). Specifically, we describe time course, incidence, and pharmacological management of OHT in eyes receiving repeated injections. Methods: Methods: this study included 78 eyes (78 patients) and 154 SIDIs injections over 3 years. Mean age: 67±13.4 SD, 48 males (62%) and 30 females (38%). SIDIs contained 0.7 mg of dexamethasone. Goldmann tonometry was performed at baseline (T0, before the injection) and at 1 week (T1w), 1 month (T1m), 3 months (T3m), and 6 months (T6m) after each intravitreal injection (INJ). Statistical analysis was performed using the Friedman test. Inclusion criteria: macular edema secondary to retinalI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
