Here we describe a case of a methicillin-resistant coagulase-negative staphylococci prosthetic valve endocarditis in a patient considered not eligible for valve replacement due to high perioperative mortality risk and who did not tolerate oral antibiotic treatment. Under these circumstances, intravenous long-term chronic suppressive antibiotic therapy with dalbavancin, scheduling the doses using the serum bactericidal activity titers, proved to be safe and effective.

Serum Bactericidal Activity Levels Monitor to Guide Intravenous Dalbavancin Chronic Suppressive Therapy of Inoperable Staphylococcal Prosthetic Valve Endocarditis: A Case Report / Spaziante, Martina; Franchi, Cristiana; Taliani, Gloria; D'Avolio, Antonio; Pietropaolo, Valeria; Biliotti, Elisa; Esvan, Rozenn; Venditti, Mario. - In: OPEN FORUM INFECTIOUS DISEASES. - ISSN 2328-8957. - 6:11(2019), p. ofz427. [10.1093/ofid/ofz427]

Serum Bactericidal Activity Levels Monitor to Guide Intravenous Dalbavancin Chronic Suppressive Therapy of Inoperable Staphylococcal Prosthetic Valve Endocarditis: A Case Report

Spaziante, Martina;Franchi, Cristiana;Taliani, Gloria;Pietropaolo, Valeria;Biliotti, Elisa;Esvan, Rozenn;Venditti, Mario
2019

Abstract

Here we describe a case of a methicillin-resistant coagulase-negative staphylococci prosthetic valve endocarditis in a patient considered not eligible for valve replacement due to high perioperative mortality risk and who did not tolerate oral antibiotic treatment. Under these circumstances, intravenous long-term chronic suppressive antibiotic therapy with dalbavancin, scheduling the doses using the serum bactericidal activity titers, proved to be safe and effective.
dalbavancin; long-term chronic suppressive antibiotic therapy; prosthetic valve endocarditis; serum bactericidal activity
01 Pubblicazione su rivista::01a Articolo in rivista
Serum Bactericidal Activity Levels Monitor to Guide Intravenous Dalbavancin Chronic Suppressive Therapy of Inoperable Staphylococcal Prosthetic Valve Endocarditis: A Case Report / Spaziante, Martina; Franchi, Cristiana; Taliani, Gloria; D'Avolio, Antonio; Pietropaolo, Valeria; Biliotti, Elisa; Esvan, Rozenn; Venditti, Mario. - In: OPEN FORUM INFECTIOUS DISEASES. - ISSN 2328-8957. - 6:11(2019), p. ofz427. [10.1093/ofid/ofz427]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1340551
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 16
social impact