Here we describe a case of a methicillin-resistant coagulase-negative staphylococci prosthetic valve endocarditis in a patient considered not eligible for valve replacement due to high perioperative mortality risk and who did not tolerate oral antibiotic treatment. Under these circumstances, intravenous long-term chronic suppressive antibiotic therapy with dalbavancin, scheduling the doses using the serum bactericidal activity titers, proved to be safe and effective.
Serum Bactericidal Activity Levels Monitor to Guide Intravenous Dalbavancin Chronic Suppressive Therapy of Inoperable Staphylococcal Prosthetic Valve Endocarditis: A Case Report / Spaziante, Martina; Franchi, Cristiana; Taliani, Gloria; D'Avolio, Antonio; Pietropaolo, Valeria; Biliotti, Elisa; Esvan, Rozenn; Venditti, Mario. - In: OPEN FORUM INFECTIOUS DISEASES. - ISSN 2328-8957. - 6:11(2019), p. ofz427. [10.1093/ofid/ofz427]
Serum Bactericidal Activity Levels Monitor to Guide Intravenous Dalbavancin Chronic Suppressive Therapy of Inoperable Staphylococcal Prosthetic Valve Endocarditis: A Case Report
Spaziante, Martina;Franchi, Cristiana;Taliani, Gloria;Pietropaolo, Valeria;Biliotti, Elisa;Esvan, Rozenn;Venditti, Mario
2019
Abstract
Here we describe a case of a methicillin-resistant coagulase-negative staphylococci prosthetic valve endocarditis in a patient considered not eligible for valve replacement due to high perioperative mortality risk and who did not tolerate oral antibiotic treatment. Under these circumstances, intravenous long-term chronic suppressive antibiotic therapy with dalbavancin, scheduling the doses using the serum bactericidal activity titers, proved to be safe and effective.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
