Introduction: The incidence of pheochromocytomas is about 1-2/100000 in the adult population. Nearly 10% have an extra-adrenal location or multiple locations and are defined as paragangliomas. They might be catecholamine- secreting as ordinary pheochromocytomas or clinically asymptomatic with compression symptoms. Patients and Methods: Three cases of abdominal paraganglioma with different clinical onset are reported. Discussion: Incidentally diagnosed asymptomatic retroperitoneal tumors with secondary hypertension suggest paraganglioma. Increased levels of catecholamine and extra-adrenal lesions identified at CT or MR imaging with positive MIBG scintigraphy support the diagnosis. Optimal care requires a multidisciplinary approach, accurate preoperative exact localization and adequate preoperative medical treatment to reduce perioperative cardiovascular complications.
Surgical management of extra-adrenal abdominal paragangliomas. Report of three cases and review of the literature / Polistena, A; Cavallaro, G; Cotesta, D; Petramala, L; Letizia, C; Basile, U; Filetti, S; Cavallaro, A; De Toma, G. - In: THE ENDOCRINOLOGIST. - ISSN 1051-2144. - 20:2(2010), pp. 63-65. [10.1097/TEN.0b013e3181d4bf9a]
Surgical management of extra-adrenal abdominal paragangliomas. Report of three cases and review of the literature
Polistena APrimo
Writing – Original Draft Preparation
;Petramala L;
2010
Abstract
Introduction: The incidence of pheochromocytomas is about 1-2/100000 in the adult population. Nearly 10% have an extra-adrenal location or multiple locations and are defined as paragangliomas. They might be catecholamine- secreting as ordinary pheochromocytomas or clinically asymptomatic with compression symptoms. Patients and Methods: Three cases of abdominal paraganglioma with different clinical onset are reported. Discussion: Incidentally diagnosed asymptomatic retroperitoneal tumors with secondary hypertension suggest paraganglioma. Increased levels of catecholamine and extra-adrenal lesions identified at CT or MR imaging with positive MIBG scintigraphy support the diagnosis. Optimal care requires a multidisciplinary approach, accurate preoperative exact localization and adequate preoperative medical treatment to reduce perioperative cardiovascular complications.File | Dimensione | Formato | |
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