Accumulating evidence suggests a potential role of dietary protein among nutritional factors interfering with the regulation of blood pressure. Dietary protein source (plant versus animal protein), and especially, protein composition in terms of amino acids has been postulated to interfere with mechanisms underlying the development of hypertension. Recently, mounting interest has been directed at amino acids in hypertension focusing on habitual dietary intake and their circulating levels regardless of single amino acid dietary supplementation. The aim of the present review was to summarize epidemiological evidence concerning the connection between amino acids and hypertension. Due to the large variability in methodologies used for assessing amino acid levels and heterogeneity in the results obtained, it was not possible to draw robust conclusions. Indeed, some classes of amino acids or individual amino acids showed non-causative association with blood pressure as well as the incidence of hypertension, but the evidence was far from being conclusive. Further research should be prompted for a thorough understanding of amino acid effects and synergistic actions of different amino acid classes on blood pressure regulation.

Amino acids and hypertension in adults / Poggiogalle, E.; Fontana, M.; Giusti, A. M.; Pinto, A.; Iannucci, G.; Lenzi, A.; Donini, L. M.; Fontana, Mario. - In: NUTRIENTS. - ISSN 2072-6643. - 11:7(2019), p. 1459. [10.3390/nu11071459]

Amino acids and hypertension in adults

Poggiogalle E.
;
Fontana M.;Giusti A. M.;Pinto A.;Iannucci G.;Lenzi A.;Donini L. M.;FONTANA, Mario
2019

Abstract

Accumulating evidence suggests a potential role of dietary protein among nutritional factors interfering with the regulation of blood pressure. Dietary protein source (plant versus animal protein), and especially, protein composition in terms of amino acids has been postulated to interfere with mechanisms underlying the development of hypertension. Recently, mounting interest has been directed at amino acids in hypertension focusing on habitual dietary intake and their circulating levels regardless of single amino acid dietary supplementation. The aim of the present review was to summarize epidemiological evidence concerning the connection between amino acids and hypertension. Due to the large variability in methodologies used for assessing amino acid levels and heterogeneity in the results obtained, it was not possible to draw robust conclusions. Indeed, some classes of amino acids or individual amino acids showed non-causative association with blood pressure as well as the incidence of hypertension, but the evidence was far from being conclusive. Further research should be prompted for a thorough understanding of amino acid effects and synergistic actions of different amino acid classes on blood pressure regulation.
Amino acids; blood pressure; humans
01 Pubblicazione su rivista::01a Articolo in rivista
Amino acids and hypertension in adults / Poggiogalle, E.; Fontana, M.; Giusti, A. M.; Pinto, A.; Iannucci, G.; Lenzi, A.; Donini, L. M.; Fontana, Mario. - In: NUTRIENTS. - ISSN 2072-6643. - 11:7(2019), p. 1459. [10.3390/nu11071459]
File allegati a questo prodotto
File Dimensione Formato  
Poggiogalle_Amino-acids_2019.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 241.83 kB
Formato Adobe PDF
241.83 kB Adobe PDF Visualizza/Apri PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1321706
Citazioni
  • ???jsp.display-item.citation.pmc??? 10
  • Scopus 23
  • ???jsp.display-item.citation.isi??? 20
social impact