Hematophagous arthropods during feeding inject into their hosts a cocktail of salivary proteins whose main role is to allow for an effective blood meal by counteracting host hemostasis, inflammation and immunity. However, saliva of blood feeders also evokes in vertebrates an antibody response that can be used to evaluate exposure to disease vectors. Salivary transcriptome studies carried out in different hematophagous species in the last fifteen years clarified the complexity of the salivary repertoires of blood feeding arthropods, pointing out that salivary proteins evolve at a fast evolutionary rate and highlighting the existence of family-, genus- and sometime even species-specific salivary proteins. Focusing on mosquitoes of the genera Anopheles and Aedes, which are important vectors of the human malaria parasite Plasmodium falciparum and of several arboviruses, we summarize here recent efforts to exploit genus-specific salivary proteins as biomarkers of human exposure to these vectors of large relevance for public health.

Antigeni salivari quali strumenti epidemiologici per la valutazione dell'esposizione umana ad Aedes albopictus / Arca', Bruno; Buezo Montero, Sara; Lombardo, Fabrizio. - In: ATTI DELL'ACCADEMIA NAZIONALE ITALIANA DI ENTOMOLOGIA. RENDICONTI. - ISSN 0065-0757. - Anno LXVI:(2019), pp. 123-128. ((Intervento presentato al convegno Tavola Rotonda su: APPROCCI GENOMICI E MOLECOLARI PER IL CONTROLLO DI SPECIE INVASIVE DI INSETTI DI INTERESSE AGRARIO E SANITARIO. tenutosi a FIRENZE.

Antigeni salivari quali strumenti epidemiologici per la valutazione dell'esposizione umana ad Aedes albopictus

Bruno Arcà
;
Sara Buezo Montero;Fabrizio Lombardo
2019

Abstract

Hematophagous arthropods during feeding inject into their hosts a cocktail of salivary proteins whose main role is to allow for an effective blood meal by counteracting host hemostasis, inflammation and immunity. However, saliva of blood feeders also evokes in vertebrates an antibody response that can be used to evaluate exposure to disease vectors. Salivary transcriptome studies carried out in different hematophagous species in the last fifteen years clarified the complexity of the salivary repertoires of blood feeding arthropods, pointing out that salivary proteins evolve at a fast evolutionary rate and highlighting the existence of family-, genus- and sometime even species-specific salivary proteins. Focusing on mosquitoes of the genera Anopheles and Aedes, which are important vectors of the human malaria parasite Plasmodium falciparum and of several arboviruses, we summarize here recent efforts to exploit genus-specific salivary proteins as biomarkers of human exposure to these vectors of large relevance for public health.
Tavola Rotonda su: APPROCCI GENOMICI E MOLECOLARI PER IL CONTROLLO DI SPECIE INVASIVE DI INSETTI DI INTERESSE AGRARIO E SANITARIO.
blood feeding; salivary proteins; biomarkers; anopheles; aedes
04 Pubblicazione in atti di convegno::04c Atto di convegno in rivista
Antigeni salivari quali strumenti epidemiologici per la valutazione dell'esposizione umana ad Aedes albopictus / Arca', Bruno; Buezo Montero, Sara; Lombardo, Fabrizio. - In: ATTI DELL'ACCADEMIA NAZIONALE ITALIANA DI ENTOMOLOGIA. RENDICONTI. - ISSN 0065-0757. - Anno LXVI:(2019), pp. 123-128. ((Intervento presentato al convegno Tavola Rotonda su: APPROCCI GENOMICI E MOLECOLARI PER IL CONTROLLO DI SPECIE INVASIVE DI INSETTI DI INTERESSE AGRARIO E SANITARIO. tenutosi a FIRENZE.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1319807
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