Resveratrol (3,5,4'-trihydroxystilbene) is one of the most abundant polyphenols in red grapes, and red wine represents one of the most important dietary source of this compound. Although its beneficial properties on human health have been widely investigated over the last 30 years, very little is known about its derivatives. Resveratrol can indeed undergo glycosylation, oligomerization and, upon UV-light exposure, it can isomerize from the trans- to the cis-isomer, which can further cyclize to 2,4,6-trihydroxyphenanthrene (THP). Although the effects of THP on human health are not yet known, being a polycyclic aromatic hydrocarbon, it can be potentially harmful. Since no data about THP occurrence in plant food and beverages are available, a simple procedure based on liquid-liquid extraction and GC-MS has been developed and validated for the simultaneous qualitative and quantitative analysis of trans-resveratrol, cis-resveratrol and THP in red wine, before and after UV-light exposure.

A gas chromatographic–mass spectrometric method for the simultaneous determination of resveratrol isomers and 2,4,6-trihydroxyphenanthrene in red wines exposed to UV-light / Francioso, Antonio; Laštovičková, Lenka; Mosca, Luciana; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - 67:(2019), pp. 11752-11757. [10.1021/acs.jafc.9b05992]

A gas chromatographic–mass spectrometric method for the simultaneous determination of resveratrol isomers and 2,4,6-trihydroxyphenanthrene in red wines exposed to UV-light

Francioso, Antonio
Co-primo
Conceptualization
;
Mosca, Luciana
Writing – Review & Editing
;
Boffi, Alberto
Funding Acquisition
;
Bonamore, Alessandra
Penultimo
Writing – Original Draft Preparation
;
Macone, Alberto
Ultimo
Project Administration
2019

Abstract

Resveratrol (3,5,4'-trihydroxystilbene) is one of the most abundant polyphenols in red grapes, and red wine represents one of the most important dietary source of this compound. Although its beneficial properties on human health have been widely investigated over the last 30 years, very little is known about its derivatives. Resveratrol can indeed undergo glycosylation, oligomerization and, upon UV-light exposure, it can isomerize from the trans- to the cis-isomer, which can further cyclize to 2,4,6-trihydroxyphenanthrene (THP). Although the effects of THP on human health are not yet known, being a polycyclic aromatic hydrocarbon, it can be potentially harmful. Since no data about THP occurrence in plant food and beverages are available, a simple procedure based on liquid-liquid extraction and GC-MS has been developed and validated for the simultaneous qualitative and quantitative analysis of trans-resveratrol, cis-resveratrol and THP in red wine, before and after UV-light exposure.
2019
resveratrol; 2,4,6-trihydroxyphenanthrene; GC-MS; red wine
01 Pubblicazione su rivista::01a Articolo in rivista
A gas chromatographic–mass spectrometric method for the simultaneous determination of resveratrol isomers and 2,4,6-trihydroxyphenanthrene in red wines exposed to UV-light / Francioso, Antonio; Laštovičková, Lenka; Mosca, Luciana; Boffi, Alberto; Bonamore, Alessandra; Macone, Alberto. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - 67:(2019), pp. 11752-11757. [10.1021/acs.jafc.9b05992]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1316071
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