Context: Management of bladder cancer (BC) is primarily driven by stage, grade, and biological potential. Knowledge of each is derived using clinical, histopathological, and radiological investigations. This multimodal approach reduces the risk of error from one particular test, but may present a staging dilemma when results conflict. Multiparametric magnetic resonance imaging (mpMRI) may improve patient care through imaging of the bladder with better resolution of the tissue planes than computed tomography and without radiation exposure. Objective: To define a standardized approach to imaging and reporting mpMRI for BC, by developing a VI-RADS score. Evidence acquisition: We created VI-RADS (Vesical Imaging-Reporting And Data System) through consensus using existing literature. Evidence synthesis: We describe standard imaging protocols and reporting criteria (including size, location, multiplicity, and morphology) for bladder mpMRI. We propose a five-point VI-RADS score, derived using T2-weighted MRI, diffusion-weighted imaging, and dynamic contrast enhancement, which suggests the risks of muscle invasion. We include sample images used to understand VI-RADS. Conclusions: We hope that VI-RADS will standardize reporting, facilitate comparisons between patients, and in future years, will be tested and refined if necessary. While we do not advocate mpMRI for all patients with BC, this imaging may compliment pathology or reduce radiation-based imaging. Bladder mpMRI may be most useful in patients with non–muscle-invasive cancers, in expediting radical treatment or for determining response to bladder-sparing approaches. Patient summary: Magnetic resonance imaging (MRI) scans for bladder cancer are becoming more common and may provide accurate information that helps improve patient care. Here, we describe a standardized reporting criterion for bladder MRI. This should improve communication between doctors and allow better comparisons between patients. Magnetic resonance imaging (MRI) scans for bladder cancer are becoming more common and may provide accurate information that helps improve patient care. Here, we describe a standardized reporting criterion for bladder MRI. This should improve communication between doctors and allow better comparisons between patients.

Multiparametric magnetic resonance imaging for bladder cancer: development of VI-RADS (Vesical Imaging-Reporting And Data System) / Panebianco, V.; Narumi, Y.; Altun, E.; Bochner, B. H.; Efstathiou, J. A.; Hafeez, S.; Huddart, R.; Kennish, S.; Lerner, S.; Montironi, R.; Muglia, V. F.; Salomon, G.; Thomas, S.; Vargas, H. A.; Witjes, J. A.; Takeuchi, M.; Barentsz, J.; Catto, J. W. F.. - In: EUROPEAN UROLOGY. - ISSN 0302-2838. - 74:3(2018), pp. 294-306. [10.1016/j.eururo.2018.04.029]

Multiparametric magnetic resonance imaging for bladder cancer: development of VI-RADS (Vesical Imaging-Reporting And Data System)

Panebianco V.;
2018

Abstract

Context: Management of bladder cancer (BC) is primarily driven by stage, grade, and biological potential. Knowledge of each is derived using clinical, histopathological, and radiological investigations. This multimodal approach reduces the risk of error from one particular test, but may present a staging dilemma when results conflict. Multiparametric magnetic resonance imaging (mpMRI) may improve patient care through imaging of the bladder with better resolution of the tissue planes than computed tomography and without radiation exposure. Objective: To define a standardized approach to imaging and reporting mpMRI for BC, by developing a VI-RADS score. Evidence acquisition: We created VI-RADS (Vesical Imaging-Reporting And Data System) through consensus using existing literature. Evidence synthesis: We describe standard imaging protocols and reporting criteria (including size, location, multiplicity, and morphology) for bladder mpMRI. We propose a five-point VI-RADS score, derived using T2-weighted MRI, diffusion-weighted imaging, and dynamic contrast enhancement, which suggests the risks of muscle invasion. We include sample images used to understand VI-RADS. Conclusions: We hope that VI-RADS will standardize reporting, facilitate comparisons between patients, and in future years, will be tested and refined if necessary. While we do not advocate mpMRI for all patients with BC, this imaging may compliment pathology or reduce radiation-based imaging. Bladder mpMRI may be most useful in patients with non–muscle-invasive cancers, in expediting radical treatment or for determining response to bladder-sparing approaches. Patient summary: Magnetic resonance imaging (MRI) scans for bladder cancer are becoming more common and may provide accurate information that helps improve patient care. Here, we describe a standardized reporting criterion for bladder MRI. This should improve communication between doctors and allow better comparisons between patients. Magnetic resonance imaging (MRI) scans for bladder cancer are becoming more common and may provide accurate information that helps improve patient care. Here, we describe a standardized reporting criterion for bladder MRI. This should improve communication between doctors and allow better comparisons between patients.
2018
Bladder cancer; multiparametric magnetic resonance imaging; RADS; scoring; staging; consensus; contrast media; diffusion magnetic resonance imaging; humans; image interpretation; computer-assisted; neoplasm staging; observer variation; predictive value of tests; reproducibility of results; urinary bladder neoplasms; data systems
01 Pubblicazione su rivista::01a Articolo in rivista
Multiparametric magnetic resonance imaging for bladder cancer: development of VI-RADS (Vesical Imaging-Reporting And Data System) / Panebianco, V.; Narumi, Y.; Altun, E.; Bochner, B. H.; Efstathiou, J. A.; Hafeez, S.; Huddart, R.; Kennish, S.; Lerner, S.; Montironi, R.; Muglia, V. F.; Salomon, G.; Thomas, S.; Vargas, H. A.; Witjes, J. A.; Takeuchi, M.; Barentsz, J.; Catto, J. W. F.. - In: EUROPEAN UROLOGY. - ISSN 0302-2838. - 74:3(2018), pp. 294-306. [10.1016/j.eururo.2018.04.029]
File allegati a questo prodotto
File Dimensione Formato  
Panebianco_Bladder-cancer.pdf

accesso aperto

Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 2.13 MB
Formato Adobe PDF
2.13 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1315207
Citazioni
  • ???jsp.display-item.citation.pmc??? 101
  • Scopus 355
  • ???jsp.display-item.citation.isi??? 298
social impact