A straightforward approach to the synthesis of challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones through the palladium-catalyzed direct arylation of N-benzyl and NH-free[1,2-c]quinazolin-6(5H)-ones with aryl bromides and chlorides is described.
Palladium-catalyzed C12-selective direct arylation of [1,2-c] quinazolin-6(5H)-ones / Arcadi, Antonio; Cacchi, Sandro; Fabrizi, Giancarlo; Fochetti, Andrea; Ghirga, Francesca; Goggiamani, Antonella; Iazzetti, Antonia; Marinelli, Fabio. - In: SYNTHESIS. - ISSN 0039-7881. - 51:17(2019), pp. 3287-3294. [10.1055/s-0037-1610711]
Palladium-catalyzed C12-selective direct arylation of [1,2-c] quinazolin-6(5H)-ones
Arcadi, Antonio;Cacchi, Sandro;Fabrizi, Giancarlo;Fochetti, Andrea;Ghirga, Francesca;Goggiamani, Antonella
;Iazzetti, Antonia
;
2019
Abstract
A straightforward approach to the synthesis of challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones through the palladium-catalyzed direct arylation of N-benzyl and NH-free[1,2-c]quinazolin-6(5H)-ones with aryl bromides and chlorides is described.File allegati a questo prodotto
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