Testing for hepatitis C virus by ELISA requires confirmation by recombinant immunoblot assay (RIBA). The first-generation RIBA uses the same antigen as used in the ELISA and one further antigen. A second-generation RIBA in which two further antigens are present, detects positivity that is not found by either the ELISA or the original RIBA. Consequently, although it is adequate to test Elisa positive sera with the first-generation RIBA, the second-generation assay is recommended for confirming negativity.

RECOMBINANT IMMUNOBLOT ASSAY FOR HEPATITIS-C VIRUS-ANTIBODY IN CHRONIC HEPATITIS / G., Taliani; M. C., Badolato; R., Lecce; C., De Bac; E., De Marzio; C., Balsano; Artini, Marco; Levrero, Massimo. - In: ARCHIVES OF VIROLOGY. - ISSN 0304-8608. - 4:4(1992), pp. 232-233.

RECOMBINANT IMMUNOBLOT ASSAY FOR HEPATITIS-C VIRUS-ANTIBODY IN CHRONIC HEPATITIS

ARTINI, Marco;LEVRERO, Massimo
1992

Abstract

Testing for hepatitis C virus by ELISA requires confirmation by recombinant immunoblot assay (RIBA). The first-generation RIBA uses the same antigen as used in the ELISA and one further antigen. A second-generation RIBA in which two further antigens are present, detects positivity that is not found by either the ELISA or the original RIBA. Consequently, although it is adequate to test Elisa positive sera with the first-generation RIBA, the second-generation assay is recommended for confirming negativity.
1992
01 Pubblicazione su rivista::01a Articolo in rivista
RECOMBINANT IMMUNOBLOT ASSAY FOR HEPATITIS-C VIRUS-ANTIBODY IN CHRONIC HEPATITIS / G., Taliani; M. C., Badolato; R., Lecce; C., De Bac; E., De Marzio; C., Balsano; Artini, Marco; Levrero, Massimo. - In: ARCHIVES OF VIROLOGY. - ISSN 0304-8608. - 4:4(1992), pp. 232-233.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/131388
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