Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.
Apium plants. Beyond simple food and phytopharmacological applications / Salehi, Bahare; Venditti, Alessandro; Frezza, Claudio; Yücetepe, Aysun; Altunta¸ Sibel Uluata, Ümit; Butnariu, Monica; Sarac, Ioan; Shaheen, Shabnum; Petropoulos, Spyridon A.; Matthews, Karl R.; Sibel Kılıç, Ceyda; Atanassova, Maria; Oluwaseun Adetunji, Charles; Oluwaseun Ademiluyi, Adedayo; Özçelik, Beraat; Valere Tsouh Fokou, Patrick; Martins, Natália; Cho, William C.; Sharifi-Rad, Javad. - In: APPLIED SCIENCES. - ISSN 2076-3417. - 9:17(2019), pp. 1-39. [10.3390/app9173547]
Apium plants. Beyond simple food and phytopharmacological applications
Alessandro Venditti;Claudio Frezza;
2019
Abstract
Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.| File | Dimensione | Formato | |
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