In this paper, the viscoelastic characterization of biosamples is addressed considering a measuring technique relying on the use of a MEMS techonology-based microgripper. A proper mechanical model is developed for the coupled nonlinear dynamics of the microsystem, composed of the measuring tool and the specimen to be analyzed. The Maxwell liquid drop model and the generalized Maxwell-Wiechert model are considered for the sample, and the identification of the viscoelastic parameters is performed by implementing a genetic algorithm.

A genetic algorithm-based method for the mechanical characterization of biosamples using a MEMS microgripper: numerical simulations / Verotti, M.; Di Giamberardino, P.; Belfiore, N. P.; Giannini, O.. - In: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. - ISSN 1751-6161. - 96:(2019), pp. 88-95. [10.1016/j.jmbbm.2019.04.023]

A genetic algorithm-based method for the mechanical characterization of biosamples using a MEMS microgripper: numerical simulations

Verotti M.
Primo
;
Di Giamberardino P.
Secondo
;
Belfiore N. P.
Penultimo
;
Giannini O.
Ultimo
2019

Abstract

In this paper, the viscoelastic characterization of biosamples is addressed considering a measuring technique relying on the use of a MEMS techonology-based microgripper. A proper mechanical model is developed for the coupled nonlinear dynamics of the microsystem, composed of the measuring tool and the specimen to be analyzed. The Maxwell liquid drop model and the generalized Maxwell-Wiechert model are considered for the sample, and the identification of the viscoelastic parameters is performed by implementing a genetic algorithm.
2019
biosamples analysis; genetic algorithms; MEMS microgripper; micromanipulation; parameters estimation; viscoelastic characterization
01 Pubblicazione su rivista::01a Articolo in rivista
A genetic algorithm-based method for the mechanical characterization of biosamples using a MEMS microgripper: numerical simulations / Verotti, M.; Di Giamberardino, P.; Belfiore, N. P.; Giannini, O.. - In: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. - ISSN 1751-6161. - 96:(2019), pp. 88-95. [10.1016/j.jmbbm.2019.04.023]
File allegati a questo prodotto
File Dimensione Formato  
Verotti_A-genetic-algorithm-based_2019.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 1.75 MB
Formato Adobe PDF
1.75 MB Adobe PDF   Contatta l'autore
Verotti_preprint_A-genetic-algorithm-based_2019.pdf

accesso aperto

Note: https://www.sciencedirect.com/science/article/abs/pii/S1751616118311810
Tipologia: Documento in Pre-print (manoscritto inviato all'editore, precedente alla peer review)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 837.64 kB
Formato Adobe PDF
837.64 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1308999
Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 24
  • ???jsp.display-item.citation.isi??? 20
social impact