Giant Cell Arteritis (GCA), or Horton’s Arteritis, is a chronic form of vasculitis of the large and medium vessels, especially involving the extracranial branches of the carotid arteries, in particular, the temporal artery, with the involvement of the axillary, femoral and iliac arteries too. Arterial wall inflammation leads to luminal occlusion and tissue ischemia, which is responsible for the clinical manifestations of the disease. A substantial number of patients affected by GCA present head and neck symptoms, including ocular, neurological and otorhinolaryngological manifestations. The aim of this article is to present pathogenesis, clinical aspects and treatment approaches of GCA manifestations.

Giant cell arteritis (GCA): pathogenesis, clinical aspects and treatment approaches / CIOFALO, Andrea; GULOTTA, GIAMPIERO; IANNELLA, GIANNICOLA; PASQUARIELLO, BENEDETTA; MANNO, ALESSANDRA; ANGELETTI, DILETTA; PACE, ANNALISA; GRECO, Antonio; ALTISSIMI, Giancarlo; DE VINCENTIIS, Marco; MAGLIULO, Giuseppe. - In: CURRENT RHEUMATOLOGY REVIEWS. - ISSN 1573-3971. - 15:4(2019), pp. 259-268. [10.2174/1573397115666190227194014]

Giant cell arteritis (GCA): pathogenesis, clinical aspects and treatment approaches

Andrea Ciofalo
Primo
;
Giampiero Gulotta
Secondo
;
Giannicola Iannella;Benedetta Pasquariello;Alessandra Manno;Diletta Angeletti;Annalisa Pace;Antonio Greco;Giancarlo Altissimi;Marco de Vincentiis
Penultimo
;
Giuseppe Magliulo.
Ultimo
2019

Abstract

Giant Cell Arteritis (GCA), or Horton’s Arteritis, is a chronic form of vasculitis of the large and medium vessels, especially involving the extracranial branches of the carotid arteries, in particular, the temporal artery, with the involvement of the axillary, femoral and iliac arteries too. Arterial wall inflammation leads to luminal occlusion and tissue ischemia, which is responsible for the clinical manifestations of the disease. A substantial number of patients affected by GCA present head and neck symptoms, including ocular, neurological and otorhinolaryngological manifestations. The aim of this article is to present pathogenesis, clinical aspects and treatment approaches of GCA manifestations.
2019
autoimmune disease; giant cell arteritis; ENT; audiovestibular abnormalities; hearing loss
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Giant cell arteritis (GCA): pathogenesis, clinical aspects and treatment approaches / CIOFALO, Andrea; GULOTTA, GIAMPIERO; IANNELLA, GIANNICOLA; PASQUARIELLO, BENEDETTA; MANNO, ALESSANDRA; ANGELETTI, DILETTA; PACE, ANNALISA; GRECO, Antonio; ALTISSIMI, Giancarlo; DE VINCENTIIS, Marco; MAGLIULO, Giuseppe. - In: CURRENT RHEUMATOLOGY REVIEWS. - ISSN 1573-3971. - 15:4(2019), pp. 259-268. [10.2174/1573397115666190227194014]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1292576
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