Herein, we describe our clinical experience on the management of patients with ectopic breast tissue. Ectopic breast cancers are rare neoplasms that occur in 0.3% to 0.6% of all cases of breast cancer. Overall, we retrospectively reviewed 327 of 12,177 (2.7%) patients with ectopic breast tissue, observed throughout 20 years and classified according to the classification of Kajava. Among these patients, 4 malignancies were diagnosed. We recommend an earlier surgical approach for patients with lesions from class I to IV. Background Ectopic breast tissue, which includes both supernumerary breast and aberrant breast tissue, is the most common congenital breast abnormality. Ectopic breast cancers are rare neoplasms that occur in 0.3% to 0.6% of all cases of breast cancer. Patients and Methods We retrospectively report, using a large series of breast abnormalities diagnosed and treated, our clinical experience on the management of the ectopic breast cancer. In 2 decades, we observed 327 (2.7%) patients with ectopic breast tissue out of a total of 12,177 subjects undergoing a breast visit for lesions. All patients were classified into 8 classes, according to the classification of Kajava, and assessed by a physician examination, ultrasounds, and, when appropriate, further studies with fine needle aspiration cytology and mammography. All specimens were submitted to the anatomo-pathologist. The most frequent benign histological diagnosis was fibrocystic disease. A rare granulosa cell tumor was also found in the right anterior thoracic wall of 1 patient. Four malignancies were also diagnosed in 4 women: an infiltrating lobular cancer in 1 patient with a lesion classified as class I, and an infiltrating apocrine carcinoma, an infiltrating ductal cancer, and an infiltrating ductal cancer with tubular pattern, occurring in 3 patients with lesions classified as class IV. Only 1 recurrence was observed. We recommend an earlier surgical approach for patients with lesions from class I to IV.

Prevalence of ectopic breast tissue and tumor: a 20-year single center experience / Fama, F.; Cicciu, M.; Sindoni, A.; Scarfo, P.; Pollicino, A.; Giacobbe, G.; Buccheri, G.; Taranto, F.; Palella, J.; Gioffre-Florio, M.. - In: CLINICAL BREAST CANCER. - ISSN 1526-8209. - 16:4(2016), pp. e107-e112. [10.1016/j.clbc.2016.03.004]

Prevalence of ectopic breast tissue and tumor: a 20-year single center experience

Sindoni A.;
2016

Abstract

Herein, we describe our clinical experience on the management of patients with ectopic breast tissue. Ectopic breast cancers are rare neoplasms that occur in 0.3% to 0.6% of all cases of breast cancer. Overall, we retrospectively reviewed 327 of 12,177 (2.7%) patients with ectopic breast tissue, observed throughout 20 years and classified according to the classification of Kajava. Among these patients, 4 malignancies were diagnosed. We recommend an earlier surgical approach for patients with lesions from class I to IV. Background Ectopic breast tissue, which includes both supernumerary breast and aberrant breast tissue, is the most common congenital breast abnormality. Ectopic breast cancers are rare neoplasms that occur in 0.3% to 0.6% of all cases of breast cancer. Patients and Methods We retrospectively report, using a large series of breast abnormalities diagnosed and treated, our clinical experience on the management of the ectopic breast cancer. In 2 decades, we observed 327 (2.7%) patients with ectopic breast tissue out of a total of 12,177 subjects undergoing a breast visit for lesions. All patients were classified into 8 classes, according to the classification of Kajava, and assessed by a physician examination, ultrasounds, and, when appropriate, further studies with fine needle aspiration cytology and mammography. All specimens were submitted to the anatomo-pathologist. The most frequent benign histological diagnosis was fibrocystic disease. A rare granulosa cell tumor was also found in the right anterior thoracic wall of 1 patient. Four malignancies were also diagnosed in 4 women: an infiltrating lobular cancer in 1 patient with a lesion classified as class I, and an infiltrating apocrine carcinoma, an infiltrating ductal cancer, and an infiltrating ductal cancer with tubular pattern, occurring in 3 patients with lesions classified as class IV. Only 1 recurrence was observed. We recommend an earlier surgical approach for patients with lesions from class I to IV.
2016
Aberrant breast tissue; Ectopic breast cancer; Polymastia; Polythelia; Supernumerary breast; Adolescent; Adult; Aged; Aged, 80 and over; Biopsy, Fine-Needle; Breast; Breast Diseases; Breast Neoplasms; Breast Neoplasms, Male; Choristoma; Female; Fibrocystic Breast Disease; Humans; Male; Mammography; Middle Aged; Neoplasm Recurrence, Local; Nipples; Prevalence; Retrospective Studies; Ultrasonography, Mammary; Young Adult
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Prevalence of ectopic breast tissue and tumor: a 20-year single center experience / Fama, F.; Cicciu, M.; Sindoni, A.; Scarfo, P.; Pollicino, A.; Giacobbe, G.; Buccheri, G.; Taranto, F.; Palella, J.; Gioffre-Florio, M.. - In: CLINICAL BREAST CANCER. - ISSN 1526-8209. - 16:4(2016), pp. e107-e112. [10.1016/j.clbc.2016.03.004]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1289279
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