Multidrug resistance plasmids carrying the blaCMY-2 gene have been identified in Salmonella enterica serovars Typhimurium and Newport from the United States. This gene confers decreased susceptibility to ceftriaxone, and is most often found in strains with concomitant resistance to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole and tetracycline. The bla CMY-2-carrying plasmids studied here were shown to also carry the florfenicol resistance gene, floR, on a genetic structure previously identified in Escherichia coli plasmids in Europe. These data indicate that the use of different antimicrobial agents, including phenicols, may serve to maintain multidrug resistance plasmids on which extended-spectrum cephalosporin resistance determinants co-exist with other resistance genes in Salmonella. © 2004 Published by Elsevier B.V. on behalf of the Federation of European Microbiological Societies.
Plasmid-mediated florfenicol and ceftriaxone resistance encoded by the floR and blaCMY-2 genes in Salmonella enterica serovars Typhimurium and Newport isolated in the United States / Doublet, B; Carattoli, A; Whichard, Jm; White, Dg; Baucheron, S; Chaslus-Dancla, E; Cloeckaert, A.. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 1574-6968. - 233:2(2004), pp. 301-305. [10.1016/j.femsle.2004.02.023]
Plasmid-mediated florfenicol and ceftriaxone resistance encoded by the floR and blaCMY-2 genes in Salmonella enterica serovars Typhimurium and Newport isolated in the United States
Carattoli A;
2004
Abstract
Multidrug resistance plasmids carrying the blaCMY-2 gene have been identified in Salmonella enterica serovars Typhimurium and Newport from the United States. This gene confers decreased susceptibility to ceftriaxone, and is most often found in strains with concomitant resistance to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole and tetracycline. The bla CMY-2-carrying plasmids studied here were shown to also carry the florfenicol resistance gene, floR, on a genetic structure previously identified in Escherichia coli plasmids in Europe. These data indicate that the use of different antimicrobial agents, including phenicols, may serve to maintain multidrug resistance plasmids on which extended-spectrum cephalosporin resistance determinants co-exist with other resistance genes in Salmonella. © 2004 Published by Elsevier B.V. on behalf of the Federation of European Microbiological Societies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
