We characterized 20 Shigella isolates with decreased susceptibility to fluoroquinolones. Most patients (80%) from whom a travel history was obtained reported travel to South or Southeast Asia. Mutations within the quinolone resistance determining regions of gyrA and parC and plasmid-mediated resistance determinants (qnrB, qnrS, and aac(6′)-Ib-cr) were identified. The rise in antimicrobial resistance among Shigella isolates may necessitate the increased use of extended-spectrum cephalosporins or macrolides in some patients. Copyright © 2011, American Society for Microbiology. All Rights Reserved.
Decreased susceptibility to ciprofloxacin among Shigella isolates in the United States, 2006 to 2009 / Folster, J. P.; Pecic, G; Bowen, A; Rickert, R; Carattoli, A; Whichard, J. M.. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - 55:4(2011), pp. 1758-1760. [10.1128/AAC.01463-10]
Decreased susceptibility to ciprofloxacin among Shigella isolates in the United States, 2006 to 2009
Carattoli A;
2011
Abstract
We characterized 20 Shigella isolates with decreased susceptibility to fluoroquinolones. Most patients (80%) from whom a travel history was obtained reported travel to South or Southeast Asia. Mutations within the quinolone resistance determining regions of gyrA and parC and plasmid-mediated resistance determinants (qnrB, qnrS, and aac(6′)-Ib-cr) were identified. The rise in antimicrobial resistance among Shigella isolates may necessitate the increased use of extended-spectrum cephalosporins or macrolides in some patients. Copyright © 2011, American Society for Microbiology. All Rights Reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
