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We evaluated the pet food contained in 30 packages as a potential origin of extended-spectrum cephalosporin-resistant Gramnegative organisms and β-lactamase genes (bla). Live bacteria were not detected by selective culture. However, PCR investigations on food DNA extracts indicated that samples harbored the blaCTX-M-15(53.3%), blaCMY-4(20%), and blaVEB-4-like(6.7%) genes. Particularly worrisome was the presence of blaOXA-48-likecarbapenemases (13.3%). The original pet food ingredients and/or the production processes were highly contaminated with bacteria carrying clinically relevant acquired bla genes. © 2014 American Society for Microbiology. All Right Reserved.

High prevalence of extended-spectrum β-lactamase, plasmid-mediated AmpC, and carbapenemase genes in pet food / Seiffert, Sn; Carattoli, A; ., Tinguely R; Lupo, ; Perreten, V; Endimiani, A.. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - 58:10(2014), pp. 6320-6323.

High prevalence of extended-spectrum β-lactamase, plasmid-mediated AmpC, and carbapenemase genes in pet food

Carattoli A;
2014

Abstract

We evaluated the pet food contained in 30 packages as a potential origin of extended-spectrum cephalosporin-resistant Gramnegative organisms and β-lactamase genes (bla). Live bacteria were not detected by selective culture. However, PCR investigations on food DNA extracts indicated that samples harbored the blaCTX-M-15(53.3%), blaCMY-4(20%), and blaVEB-4-like(6.7%) genes. Particularly worrisome was the presence of blaOXA-48-likecarbapenemases (13.3%). The original pet food ingredients and/or the production processes were highly contaminated with bacteria carrying clinically relevant acquired bla genes. © 2014 American Society for Microbiology. All Right Reserved.
2014
carbapenemase; cephalosporin; extended spectrum beta lactamase; antiinfective agent; bacterial protein; beta lactamase; carbapenemase; ampicillin; bacterial DNA; beta lactamase AmpC; beta lactamase CTX M; cefotaxime; ceftazidime; extended spectrum beta lactamase, animal food; antibiotic resistance; Article; bacterium contamination; bacterium culture; DNA isolation; nonhuman; plasmid; polymerase chain reaction; drug effects; genetics; Gram negative bacterium; microbial sensitivity test; antibiotic resistance; bacterial gene; bacterium contamination; bacterium detection; bacterium isolate; comparative study; controlled study; DNA extraction; DNA sequence; extended spectrum beta lactamase producing Enterobacteriaceae; food composition; food contamination; food processing; gene insertion sequence; Kluyvera; priority journal; Proteus mirabilis, Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Gram-Negative Bacteria; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction
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High prevalence of extended-spectrum β-lactamase, plasmid-mediated AmpC, and carbapenemase genes in pet food / Seiffert, Sn; Carattoli, A; ., Tinguely R; Lupo, ; Perreten, V; Endimiani, A.. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - 58:10(2014), pp. 6320-6323.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1284313
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