Transcranial magnetic stimulation (TMS) is a widely used technique to examine cortical physiology in intact human subjects. Depending on the stimulus parameters, TMS can be used to test several different excitatory and inhibitory circuits in the brain (Rothwell, 1997; Chen, 2000; Hallett, 2000). Changes in cortical excitatory and inhibitory circuits occur in many neurological and psychiatric disorders and may mediate cortical plasticity. In this chapter, several different measures of cortical inhibition originating mainly in the motor cortex and induced either by stimulation of the motor cortex itself or by stimulation of other central or peripheral neural structures will be briefly reviewed. The more relevant findings in some neurological diseases will be also described.
Measures of cortical inhibition in health and disease / Chen, R; Curra', Antonio. - In: CLINICAL NEUROPHYSIOLOGY. - ISSN 1388-2457. - STAMPA. - 57:Supplements to Clin Neurophys(2004), pp. 691-701. [10.1016/S1567-424X(09)70409-X]
Measures of cortical inhibition in health and disease.
CURRA', antonio
2004
Abstract
Transcranial magnetic stimulation (TMS) is a widely used technique to examine cortical physiology in intact human subjects. Depending on the stimulus parameters, TMS can be used to test several different excitatory and inhibitory circuits in the brain (Rothwell, 1997; Chen, 2000; Hallett, 2000). Changes in cortical excitatory and inhibitory circuits occur in many neurological and psychiatric disorders and may mediate cortical plasticity. In this chapter, several different measures of cortical inhibition originating mainly in the motor cortex and induced either by stimulation of the motor cortex itself or by stimulation of other central or peripheral neural structures will be briefly reviewed. The more relevant findings in some neurological diseases will be also described.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
