Few topics have elicited more emotion than the issue of screening for vitamin D status and the discussion on the need for global supplementation with vitamin D metabolites. The importance of the problem is highlighted by the USPSTF posted draft research plan with the aim of making an update recommendations statement, possibly next year. Here, we discuss two different viewpoints on screening for vitamin D status: for and against. In the literature there are scientifically sound opinions supporting pro and cons positions. However, we believe that the best way to definitively elucidate this issue is the implementation of a randomized controlled trial evaluating clinical outcomes or harms in persons screened versus those not screened for vitamin D defi ciency. The feasibility of such a trial is probably questionable owing to uncertainties still present concerning th reshold for vitamin D sufficiency and end points (that is, for example, improved bone mineral density, reduced risk of falls and so on) to be reached.
Screening for hypovitaminosis D: Cost-effective or not? / Minisola, Salvatore; Colangelo, Luciano; Cipriani, Cristiana; Pepe, Jessica; Cook, Dane; Mathieu, Chantal. - In: EUROPEAN JOURNAL OF ENDOCRINOLOGY. - ISSN 0804-4643. - 180:3(2019), pp. D1-D7. [10.1530/EJE-18-0977]
Screening for hypovitaminosis D: Cost-effective or not?
Minisola, Salvatore
Primo
Writing – Original Draft Preparation
;Colangelo, LucianoSecondo
;Cipriani, CristianaWriting – Review & Editing
;Pepe, Jessica;
2019
Abstract
Few topics have elicited more emotion than the issue of screening for vitamin D status and the discussion on the need for global supplementation with vitamin D metabolites. The importance of the problem is highlighted by the USPSTF posted draft research plan with the aim of making an update recommendations statement, possibly next year. Here, we discuss two different viewpoints on screening for vitamin D status: for and against. In the literature there are scientifically sound opinions supporting pro and cons positions. However, we believe that the best way to definitively elucidate this issue is the implementation of a randomized controlled trial evaluating clinical outcomes or harms in persons screened versus those not screened for vitamin D defi ciency. The feasibility of such a trial is probably questionable owing to uncertainties still present concerning th reshold for vitamin D sufficiency and end points (that is, for example, improved bone mineral density, reduced risk of falls and so on) to be reached.File | Dimensione | Formato | |
---|---|---|---|
Minisola_Screening_2019_copia_autore.pdf
solo gestori archivio
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
611.1 kB
Formato
Adobe PDF
|
611.1 kB | Adobe PDF | Contatta l'autore |
Minisola_Screening_2019.pdf
solo gestori archivio
Note: https://eje.bioscientifica.com/view/journals/eje/180/3/EJE-18-0977.xml?rskey=ikvlcT&result=1
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
295.65 kB
Formato
Adobe PDF
|
295.65 kB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.