The authors compared the therapeutic effectiveness of these different pharmacological methods of preventing dysfunctional menometrorrhagia in adolescents, which were: 1) chorionic gonadotropin, 2) cyclofenil, 3) ovariostatics. Therapy was given during 2 menstrual cycles, and effects were evaluated both during the treatment and for the succeeding 2 cycles. Parameters followed were: a) clinical recovery, b) persistence of spotting, c) effectiveness in inducing ovulation. The results were equally good both in treatment with ovariostatics and ovulation inducers. The latter proved however, more effective during follow-up. Side-effects were very rare, so much so that, in no case was it necessary to suspend treatment.
[Medium term treatment and prophylaxis of dysfunctional metrorrhagia in adolescence] / Mossa, Bruno; Aleandri, Vincenzo; Gabriele, Novembri; Morini, Alberto. - In: MINERVA GINECOLOGICA. - ISSN 0026-4784. - STAMPA. - 41:10(1989), pp. 503-507.