The frequency of myocaridal infarction and sudden death is increased between 6 AM and noon. To determine whether the same is true for the onset of ischemic stroke, we studied 426 consecutive patients within 12 hours after the onset of their first hemispheric stroke. The frequency of onset of hemispheric stroke was significantly (p = 0.0001) higher from 6.01 AM to noon (56.1%) than from 12.01 PM to 6 PM (20.2%), from 6.01 PM to midnight (8.2%), and from 12.01 AM to 6 AM (15.5%). The identification of periods of high risk for vascular events may have important therapeutic implications, such as matching drug effects with vulnerability.
CIRCADIAN VARIATION IN THE FREQUENCY OF ISCHEMIC STROKE / Argentino, Corrado; Toni, Danilo; Rasura, Maurizia; Violi, Francesco; Sacchetti, Maria Luisa; A., Allegretta; F., Balsano; Fieschi, Cesare. - In: STROKE. - ISSN 0039-2499. - ELETTRONICO. - 21:3(1990), pp. 387-389. [10.1161/?01.str.21.3.387]
CIRCADIAN VARIATION IN THE FREQUENCY OF ISCHEMIC STROKE
ARGENTINO, Corrado;TONI, Danilo;RASURA, Maurizia;VIOLI, Francesco;SACCHETTI, Maria Luisa;FIESCHI, Cesare
1990
Abstract
The frequency of myocaridal infarction and sudden death is increased between 6 AM and noon. To determine whether the same is true for the onset of ischemic stroke, we studied 426 consecutive patients within 12 hours after the onset of their first hemispheric stroke. The frequency of onset of hemispheric stroke was significantly (p = 0.0001) higher from 6.01 AM to noon (56.1%) than from 12.01 PM to 6 PM (20.2%), from 6.01 PM to midnight (8.2%), and from 12.01 AM to 6 AM (15.5%). The identification of periods of high risk for vascular events may have important therapeutic implications, such as matching drug effects with vulnerability.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
