A modified Zimmermann reaction (detection of 17-Ketosteroids), GBN-est, has been tested for its applicability to fetal sex diagnosis between 17 and 22 weeks of gestation. In 132 pregnant women the overall reliability prediction was only 65,1%. The sensitivity of the method was found to be unequivocally too low to measure salivary androgens. While this procedure in its present form is not suitable for prenatal sex detemination, further studies might lead to a new understanding of the changes salivary steroids during pregnancy.
Fetal sex identification II. Evaluation of GBN-test / Perniola, Luigi; Morini, Alberto; Natili, M.; Buzzi, M.; Aleandri, Vincenzo. - In: PATOLOGIA E CLINICA OSTETRICA E GINECOLOGICA. - ISSN 0304-0313. - 13 (6):(1985), pp. 470-475.
Fetal sex identification II. Evaluation of GBN-test
PERNIOLA, Luigi;MORINI, Alberto;ALEANDRI, Vincenzo
1985
Abstract
A modified Zimmermann reaction (detection of 17-Ketosteroids), GBN-est, has been tested for its applicability to fetal sex diagnosis between 17 and 22 weeks of gestation. In 132 pregnant women the overall reliability prediction was only 65,1%. The sensitivity of the method was found to be unequivocally too low to measure salivary androgens. While this procedure in its present form is not suitable for prenatal sex detemination, further studies might lead to a new understanding of the changes salivary steroids during pregnancy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.