Statistical distribution of enantiomeric excesses obtained by two sets of parallel experiments of absolute asymmetric synthesis by asymmetric autocatalysis was analyzed. It has been found that experimental data give an excellent fit to a bimodal ß distribution formula, where the components are in a golden section ratio. The parameters of this higher order ß distribution were found by computer-simulated Pólya urn model experiments. The urn model experiments indicate that the Soai-autocatalysis might operate by three concerted cooperating catalytic cycles. These results may provide also a general model of asymmetric autocatalysis. © 2009 The Chemical Society of Japan.
Data-based stochastic approach to absolute asymmetric synthesis by autocatalysis / Béla, Barabas; Caglioti, Luciano; Karoly, Micskei; Gyula, Palyi. - In: BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN. - ISSN 0009-2673. - STAMPA. - 82:11(2009), pp. 1372-1376. [10.1246/bcsj.82.1372]
Data-based stochastic approach to absolute asymmetric synthesis by autocatalysis
CAGLIOTI, Luciano;
2009
Abstract
Statistical distribution of enantiomeric excesses obtained by two sets of parallel experiments of absolute asymmetric synthesis by asymmetric autocatalysis was analyzed. It has been found that experimental data give an excellent fit to a bimodal ß distribution formula, where the components are in a golden section ratio. The parameters of this higher order ß distribution were found by computer-simulated Pólya urn model experiments. The urn model experiments indicate that the Soai-autocatalysis might operate by three concerted cooperating catalytic cycles. These results may provide also a general model of asymmetric autocatalysis. © 2009 The Chemical Society of Japan.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
