Purpose: To review our experience with fetal magnetic resonance imaging (MRI) to evaluate congenital heart disease (CHD). Methods: We performed fetal MRI in 32 fetuses with an echocardiographically assessed CHD. Both direct and indirect signs of CHD were investigated. Direct signs considered were: morpho-volumetric abnormalities of the heart; malrotations; ventricular and atrial septal defects; anomalies of the origin, size and course of the great arteries. Indirect signs considered were: difficulty to recognize a "normal" anatomical structures in the reference projections; increase of the vascular size before a stenosis; hypertrophy of the papillary muscles; cardiomegaly and pericardial effusion. All MRI findings were compared with postnatal or autoptic findings. Results: MRI allowed the CHD to be visualised by direct signs in 17 fetuses, indirect signs in 5 and both direct and indirect signs in 9 fetuses, excluding the prenatal echocardiographic suspect of hypoplastic left heart syndrome in I fetus. Postnatal echocardiograms or autoptic findings confirmed a normal heart in I fetus and CHD in 31 fetuses including a single cardiac anomaly or syndrome in 19 fetuses, 2 associated cardiac abnormalities in I I and 3 cardiac anomalies in I fetus. However, in 2 fetuses MRI detected a ventricular septal defect successively disclosed by gold standard. Conclusions: MRI is a promising method for further assessment of the cardiovascular pathologies diagnosed by echocardiography, and may be a valuable tool in assessing associated extracardiac anomalies. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

Assessment of congenital heart disease (CHD): Is there a role for fetal magnetic resonance imaging (MRI)? / Manganaro, Lucia; Savelli, Sara; DI MAURIZIO, Marco; A., Perrone; Francioso, Antonella; LA BARBERA, Laura; Totaro, Porzia; Fierro, Francesca; Tomei, Alessandra; Coratella, Fabio; Giancotti, Antonella; Ballesio, Laura; Ventriglia, Flavia. - In: EUROPEAN JOURNAL OF RADIOLOGY. - ISSN 0720-048X. - STAMPA. - 72:1(2009), pp. 172-180. [10.1016/j.ejrad.2008.06.016]

Assessment of congenital heart disease (CHD): Is there a role for fetal magnetic resonance imaging (MRI)?

MANGANARO, Lucia;SAVELLI, SARA;DI MAURIZIO, MARCO;FRANCIOSO, ANTONELLA;LA BARBERA, LAURA;TOTARO, PORZIA;FIERRO, FRANCESCA;TOMEI, ALESSANDRA;CORATELLA, FABIO;GIANCOTTI, Antonella;BALLESIO, Laura;VENTRIGLIA, Flavia
2009

Abstract

Purpose: To review our experience with fetal magnetic resonance imaging (MRI) to evaluate congenital heart disease (CHD). Methods: We performed fetal MRI in 32 fetuses with an echocardiographically assessed CHD. Both direct and indirect signs of CHD were investigated. Direct signs considered were: morpho-volumetric abnormalities of the heart; malrotations; ventricular and atrial septal defects; anomalies of the origin, size and course of the great arteries. Indirect signs considered were: difficulty to recognize a "normal" anatomical structures in the reference projections; increase of the vascular size before a stenosis; hypertrophy of the papillary muscles; cardiomegaly and pericardial effusion. All MRI findings were compared with postnatal or autoptic findings. Results: MRI allowed the CHD to be visualised by direct signs in 17 fetuses, indirect signs in 5 and both direct and indirect signs in 9 fetuses, excluding the prenatal echocardiographic suspect of hypoplastic left heart syndrome in I fetus. Postnatal echocardiograms or autoptic findings confirmed a normal heart in I fetus and CHD in 31 fetuses including a single cardiac anomaly or syndrome in 19 fetuses, 2 associated cardiac abnormalities in I I and 3 cardiac anomalies in I fetus. However, in 2 fetuses MRI detected a ventricular septal defect successively disclosed by gold standard. Conclusions: MRI is a promising method for further assessment of the cardiovascular pathologies diagnosed by echocardiography, and may be a valuable tool in assessing associated extracardiac anomalies. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/121953
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