BACKGROUND: Astroblastoma is a rare glial tumour about which little is known. METHOD: We report a case of cerebral high grade astroblastoma and discuss the clinical, histopathological, surgical, radiological and prognostic features of this tumour, in the light of the pertinent literature. RESULT: Present patient had an initial histological diagnosis of glioblastoma multiforme. Three years later an histological reevaluation was performed and revealed a high grade astroblastoma. Our patient underwent surgical removal and radiotherapy; five years after the operation he is alive and without evidence of recurrence. INTERPRETATION: Classification and histogenesis of this tumour is still debated. The lack of a clinicopathological correlation makes the prognosis of this tumour unpredictable. The optimal management is not defined, but total resection and post-operative radiotherapy seem to be the effective means to treat the astroblastoma.
Cerebral astroblastoma / E., Caroli; Salvati, Maurizio; Esposito, Vincenzo; E. R., Orlando; Giangaspero, Felice. - In: ACTA NEUROCHIRURGICA. - ISSN 0001-6268. - 146:6(2004), pp. 629-633. [10.1007/s00701-004-0230-7]
Cerebral astroblastoma
SALVATI, Maurizio;ESPOSITO, Vincenzo;GIANGASPERO, FELICE
2004
Abstract
BACKGROUND: Astroblastoma is a rare glial tumour about which little is known. METHOD: We report a case of cerebral high grade astroblastoma and discuss the clinical, histopathological, surgical, radiological and prognostic features of this tumour, in the light of the pertinent literature. RESULT: Present patient had an initial histological diagnosis of glioblastoma multiforme. Three years later an histological reevaluation was performed and revealed a high grade astroblastoma. Our patient underwent surgical removal and radiotherapy; five years after the operation he is alive and without evidence of recurrence. INTERPRETATION: Classification and histogenesis of this tumour is still debated. The lack of a clinicopathological correlation makes the prognosis of this tumour unpredictable. The optimal management is not defined, but total resection and post-operative radiotherapy seem to be the effective means to treat the astroblastoma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.