Objectives: To describe our surgical technique and to report perioperative, 3-year oncological and functional outcomes of a single-center series of purely off-clamp robotic partial nephrectomy. Methods: A prospective renal cancer institutional database was queried, and data of consecutive patients treated with purely off-clamp robotic partial nephrectomy between 2010 and 2015 in a high-volume center were collected. Perioperative complications, and 3-year oncological and functional outcomes were assessed. Univariable and multivariable analyses were carried out to identify independent predictors of renal function deterioration. Results: Out of 308 patients treated, 41 (13.3%) experienced perioperative complications, 2.9% of which were Clavien grade ≥3. The 3-year local recurrence-free survival and renal cell carcinoma-specific survival rates were 99.5% and 97.9%, respectively. No patient with preoperative chronic kidney disease stage ≤3B developed severe renal function deterioration (chronic kidney disease stage 4) at 1-year follow up. At multivariable analysis, preoperative estimated glomerular filtration rate (P = 0.005) was the only independent predictor of a new-onset chronic kidney disease stage ≥3 in patients with preoperative chronic kidney disease stages 1 or 2. Conclusions: Off-clamp robotic partial nephrectomy is a safe surgical approach in tertiary referral centers, with adequate oncological outcomes and negligible impact on renal function.

Purely off-clamp robotic partial nephrectomy: Preliminary 3-year oncological and functional outcomes / Simone, Giuseppe; Misuraca, Leonardo; Tuderti, Gabriele; Minisola, Francesco; Ferriero, Mariaconsiglia; Romeo, Giuseppe; Costantini, Manuela; Al-Rawashdah, Samer F.; Guaglianone, Salvatore; Gallucci, Michele. - In: INTERNATIONAL JOURNAL OF UROLOGY. - ISSN 0919-8172. - 25:6(2018), pp. 606-614. [10.1111/iju.13580]

Purely off-clamp robotic partial nephrectomy: Preliminary 3-year oncological and functional outcomes

Misuraca, Leonardo;Tuderti, Gabriele;Minisola, Francesco;Romeo, Giuseppe;Gallucci, Michele
2018

Abstract

Objectives: To describe our surgical technique and to report perioperative, 3-year oncological and functional outcomes of a single-center series of purely off-clamp robotic partial nephrectomy. Methods: A prospective renal cancer institutional database was queried, and data of consecutive patients treated with purely off-clamp robotic partial nephrectomy between 2010 and 2015 in a high-volume center were collected. Perioperative complications, and 3-year oncological and functional outcomes were assessed. Univariable and multivariable analyses were carried out to identify independent predictors of renal function deterioration. Results: Out of 308 patients treated, 41 (13.3%) experienced perioperative complications, 2.9% of which were Clavien grade ≥3. The 3-year local recurrence-free survival and renal cell carcinoma-specific survival rates were 99.5% and 97.9%, respectively. No patient with preoperative chronic kidney disease stage ≤3B developed severe renal function deterioration (chronic kidney disease stage 4) at 1-year follow up. At multivariable analysis, preoperative estimated glomerular filtration rate (P = 0.005) was the only independent predictor of a new-onset chronic kidney disease stage ≥3 in patients with preoperative chronic kidney disease stages 1 or 2. Conclusions: Off-clamp robotic partial nephrectomy is a safe surgical approach in tertiary referral centers, with adequate oncological outcomes and negligible impact on renal function.
2018
off-clamp; oncological outcomes; partial nephrectomy; renal function; robotic; Urology
01 Pubblicazione su rivista::01a Articolo in rivista
Purely off-clamp robotic partial nephrectomy: Preliminary 3-year oncological and functional outcomes / Simone, Giuseppe; Misuraca, Leonardo; Tuderti, Gabriele; Minisola, Francesco; Ferriero, Mariaconsiglia; Romeo, Giuseppe; Costantini, Manuela; Al-Rawashdah, Samer F.; Guaglianone, Salvatore; Gallucci, Michele. - In: INTERNATIONAL JOURNAL OF UROLOGY. - ISSN 0919-8172. - 25:6(2018), pp. 606-614. [10.1111/iju.13580]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1197239
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