A multi-component Povarov reaction was used for the preparation of [4], [5] and [6]aza- and azaoxahetero helical-shaped compounds. The oxidation of the tetrahydroquinolinic primary Povarov adducts to the aromatic quinolines is mandatory to achieve a helical-shaped structure and can be carried out in a one-pot fashion with DDQ. Resolution of [5] and [6]heterohelicenes was successfully performed by chiral HPLC.

Synthesis of heterohelicenes by a catalytic multi-component povarov reaction / Viglianisi, Caterina; Biagioli, Chiara; Lippi, Martina; Pedicini, Maria; Villani, Claudio; Franzini, Roberta; Menichetti, Stefano. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2019:1(2019), pp. 164-167. [10.1002/ejoc.201801489]

Synthesis of heterohelicenes by a catalytic multi-component povarov reaction

Villani, Claudio;Franzini, Roberta;
2019

Abstract

A multi-component Povarov reaction was used for the preparation of [4], [5] and [6]aza- and azaoxahetero helical-shaped compounds. The oxidation of the tetrahydroquinolinic primary Povarov adducts to the aromatic quinolines is mandatory to achieve a helical-shaped structure and can be carried out in a one-pot fashion with DDQ. Resolution of [5] and [6]heterohelicenes was successfully performed by chiral HPLC.
catalysis; helicenes; HPLC resolution; multi-component reactions; povarov reactions; physical and theoretical chemistry; organic chemistry
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Synthesis of heterohelicenes by a catalytic multi-component povarov reaction / Viglianisi, Caterina; Biagioli, Chiara; Lippi, Martina; Pedicini, Maria; Villani, Claudio; Franzini, Roberta; Menichetti, Stefano. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2019:1(2019), pp. 164-167. [10.1002/ejoc.201801489]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1194337
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