Functional magnetic resonance imaging (fMRI) research has shown that brain arteriovenous malformations (AVMs) lead to reorganization of cortical motor areas. Since it is known that blood oxygenation level-dependent signal in fMRI may be influenced by the hemodynamic perturbation associated with the presence of the AVM, in the present study, a combined exploration with fMRI and transcranial magnetic stimulation was performed in a patient with a right rolandic AVM in order to explore the relationship between neuronal and hemodynamic activity. The combined protocol of investigation adopted in this study was able to provide significant information regarding neuronal activity of the different cortical areas that partake to post-lesional reorganization.
Neurophysiological and functional MRI evidence of reorganization of cortical motor areas in cerebral arteriovenous malformation / Caramia, Francesca; Francia, Ada; Caterina, Mainero; Tinelli, Emanuele; Maria Giuseppina, Palmieri; Colonnese, Claudio; Bozzao, Luigi; Maria Donatella, Caramia. - In: MAGNETIC RESONANCE IMAGING. - ISSN 0730-725X. - 27:10(2009), pp. 1360-1369. [10.1016/j.mri.2009.05.029]
Neurophysiological and functional MRI evidence of reorganization of cortical motor areas in cerebral arteriovenous malformation
CARAMIA, Francesca;FRANCIA, Ada;TINELLI, EMANUELE;COLONNESE, Claudio;BOZZAO, Luigi;
2009
Abstract
Functional magnetic resonance imaging (fMRI) research has shown that brain arteriovenous malformations (AVMs) lead to reorganization of cortical motor areas. Since it is known that blood oxygenation level-dependent signal in fMRI may be influenced by the hemodynamic perturbation associated with the presence of the AVM, in the present study, a combined exploration with fMRI and transcranial magnetic stimulation was performed in a patient with a right rolandic AVM in order to explore the relationship between neuronal and hemodynamic activity. The combined protocol of investigation adopted in this study was able to provide significant information regarding neuronal activity of the different cortical areas that partake to post-lesional reorganization.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
