Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow behavior. In fact, zones of low wall shear stress are vivid areas of proliferation of atherosclerosis, and in particular, in the carotid artery. In this paper a model is presented for investigating how the presence of the plaque influences the distribution of the wall shear stress. In complement to a first approach with rigid walls, an FSI model is developed as well to simulate the coupling between the blood flow and the carotid artery deformation. The results show that the presence of the plaque causes an attenuation of the WSS in the after-plaque region as well as the emergence of recirculation areas.

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach / Zouggari, Lina; Benyebka, Bou-said; Massi, Francesco; Culla, Antonio; Antoine, Millon. - In: WORLD JOURNAL OF VASCULAR SURGERY. - ISSN 2638-4574. - 1:1(2018).

The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach

Zouggari, Lina
Primo
;
Francesco Massi;Antonio Culla;
2018

Abstract

Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow behavior. In fact, zones of low wall shear stress are vivid areas of proliferation of atherosclerosis, and in particular, in the carotid artery. In this paper a model is presented for investigating how the presence of the plaque influences the distribution of the wall shear stress. In complement to a first approach with rigid walls, an FSI model is developed as well to simulate the coupling between the blood flow and the carotid artery deformation. The results show that the presence of the plaque causes an attenuation of the WSS in the after-plaque region as well as the emergence of recirculation areas.
2018
FSI; CFD; carotid; atherosclerosis
01 Pubblicazione su rivista::01a Articolo in rivista
The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach / Zouggari, Lina; Benyebka, Bou-said; Massi, Francesco; Culla, Antonio; Antoine, Millon. - In: WORLD JOURNAL OF VASCULAR SURGERY. - ISSN 2638-4574. - 1:1(2018).
File allegati a questo prodotto
File Dimensione Formato  
Zouggari_the-role-of_2018.pdf

accesso aperto

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 4.69 MB
Formato Adobe PDF
4.69 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1190550
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact