Distant metastases from thyroid cancer of follicular origin are uncommon. Treatment includes levothyroxine administration, focal treatment modalities with surgery, external radiation therapy and thermal ablation, and radioiodine in patients with uptake of 131I in their metastases. Two-thirds of distant metastases become refractory to radioiodine at some point, and when there is a significant tumor burden and documented progression on imaging, a treatment with a kinase inhibitor may provide benefits.
Treatment of refractory thyroid cancer / Berdelou, Amandine; Lamartina, Livia; Klain, Michele; Leboulleux, Sophie; Schlumberger, Martin. - In: ENDOCRINE-RELATED CANCER. - ISSN 1351-0088. - 25:4(2018), pp. R209-R223. [10.1530/ERC-17-0542]
Treatment of refractory thyroid cancer
Lamartina, Livia;Schlumberger, Martin
2018
Abstract
Distant metastases from thyroid cancer of follicular origin are uncommon. Treatment includes levothyroxine administration, focal treatment modalities with surgery, external radiation therapy and thermal ablation, and radioiodine in patients with uptake of 131I in their metastases. Two-thirds of distant metastases become refractory to radioiodine at some point, and when there is a significant tumor burden and documented progression on imaging, a treatment with a kinase inhibitor may provide benefits.| File | Dimensione | Formato | |
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Berdelou_Treatment of refractory thyroid cancer_ 2018.pdf
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