One of the main prerequisite of a therapeutic drug is to overcome a series of physiological barriers and it to be less toxic for the human. To this aim, it is necessary to find a carrying vector able to enhance drug internalization and to improve its therapeutic efficacy. Presently, biocompatible and biodegradable nanoparticles (NPs) as some effective drug delivery devices, are widely studied. In order to increase the antimicrobial and antitumor efficacy of different natural products numerous studies are in progress to evaluate different drug delivery systems (cationic liposomes, lysozyme-shelled hollow nano/microbubbles and nano/microcapsules). This delivery system would have a synergistic and additive effect decreasing the drug resistance reactions too. The present article has tried to review some of the latest research on nanocarriers in clinical care.
Design of new nanocarriers for biomedical applications / Colone, Marisa; Angiolella, Letizia; Vitali, Alberto; Serra, Stefano; Gori, Alessandro; Calcabrini, Annarica; Stringaro, Annarita. - (2018), pp. 020026-1-020026-5. (Intervento presentato al convegno NanoInnovation 2017-Conference and Exhibition tenutosi a Rome; Italy) [10.1063/1.5047780].
Design of new nanocarriers for biomedical applications
Angiolella, Letizia;
2018
Abstract
One of the main prerequisite of a therapeutic drug is to overcome a series of physiological barriers and it to be less toxic for the human. To this aim, it is necessary to find a carrying vector able to enhance drug internalization and to improve its therapeutic efficacy. Presently, biocompatible and biodegradable nanoparticles (NPs) as some effective drug delivery devices, are widely studied. In order to increase the antimicrobial and antitumor efficacy of different natural products numerous studies are in progress to evaluate different drug delivery systems (cationic liposomes, lysozyme-shelled hollow nano/microbubbles and nano/microcapsules). This delivery system would have a synergistic and additive effect decreasing the drug resistance reactions too. The present article has tried to review some of the latest research on nanocarriers in clinical care.| File | Dimensione | Formato | |
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