Esperienza a lungo termine con approccio anatomico anterogrado alla prostatectomia radicale

ABSTRACT Purpose: To evacuate the effect of an anterograde approach to radical retropubic prostatectomy (RRP, in terms of positive surgical margins (SM+). METHODS: 323 untreated patients underwent an anterograde RRP for clinically localized prostate adenocarcinoma. Spearman coefficients, Logistic univariate and multivariate analysis were used. RESULTS: The incidence of SM+ was 14,9% and in particular was 4,5% for apical, 9.0% for lateral, 0.9% for other sites 2.8% for multiple SM+. At the univariate analysis, PSA (r=0.2073,p=0.0002), pathological stage (r=0.3777, p<0.0001), seminal vesicle invasion (r=0.1453,p=0.0089) were found to be significantly associated with SM+. At the multivariate analysis, only PSA (p=0.0090) and pathological stage (p<0.0001) were significantly and independently associated with SM+ occurrence. CONCLUSION: In our experience, the anterograde approach to RRP, is associated to low SM+ rates (Urologia 2006; 73: S16-20)