Compulsive behaviors are relatively frequent complications of Parkinson’s disease (PD).1 Risk factors for compulsive behaviors in PD include novelty-seeking personality traits, depressive symptoms, young age, and cumulative dose of dopaminergic drugs, in particular dopamine agonists (DA). Although the pathophysiology of DA-mediated compulsive behaviors in PD is not completely defined at present, altered and pulsatile mesolimbic dopaminergic stimulation may play a fundamental role
Bupropion abates dopamine agonist-mediated compulsive behaviors in Parkinson's disease / Benincasa, Dario; Pellicano, Clelia; Fanciulli, Alessandra; Pontieri, FRANCESCO ERNESTO. - In: MOVEMENT DISORDERS. - ISSN 0885-3185. - 26:(2011), pp. 355-356.
Bupropion abates dopamine agonist-mediated compulsive behaviors in Parkinson's disease.
BENINCASA, DARIO;PELLICANO, CLELIA;FANCIULLI, ALESSANDRA;PONTIERI, FRANCESCO ERNESTO
2011
Abstract
Compulsive behaviors are relatively frequent complications of Parkinson’s disease (PD).1 Risk factors for compulsive behaviors in PD include novelty-seeking personality traits, depressive symptoms, young age, and cumulative dose of dopaminergic drugs, in particular dopamine agonists (DA). Although the pathophysiology of DA-mediated compulsive behaviors in PD is not completely defined at present, altered and pulsatile mesolimbic dopaminergic stimulation may play a fundamental roleI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
