The stability of RNAs represents a crucial point for cell life in that these molecules code for proteins and also play structural and regulatory functions. In this review, we will mainly focus on RNA stability and its connection with cell death and aging. In addition, we will consider the interaction of RNAs with ribonucleoprotein complexes, such as P-bodies and stress granules, as well as the role of non-coding RNAs. Finally, we will mention some correlations between RNA and diseases, considering yeast as a simple model system for the study of human cancer and neurodegenerative disorders.

RNA stability and metabolism in regulated cell death, aging and diseases / Falcone, Claudio; Mazzoni, Cristina. - In: FEMS YEAST RESEARCH. - ISSN 1567-1356. - 18:6(2018), pp. 1-7. [10.1093/femsyr/foy050]

RNA stability and metabolism in regulated cell death, aging and diseases

Claudio Falcone
Primo
;
Cristina Mazzoni
Ultimo
2018

Abstract

The stability of RNAs represents a crucial point for cell life in that these molecules code for proteins and also play structural and regulatory functions. In this review, we will mainly focus on RNA stability and its connection with cell death and aging. In addition, we will consider the interaction of RNAs with ribonucleoprotein complexes, such as P-bodies and stress granules, as well as the role of non-coding RNAs. Finally, we will mention some correlations between RNA and diseases, considering yeast as a simple model system for the study of human cancer and neurodegenerative disorders.
2018
yeast; mRNA; aging; apoptosis; regulated cell death
01 Pubblicazione su rivista::01a Articolo in rivista
RNA stability and metabolism in regulated cell death, aging and diseases / Falcone, Claudio; Mazzoni, Cristina. - In: FEMS YEAST RESEARCH. - ISSN 1567-1356. - 18:6(2018), pp. 1-7. [10.1093/femsyr/foy050]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1172769
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