The genetic anticipation phenomenon has been described in several neurological disorders, often associated with unstable trinucleotide repeats in the affected genes. The occurrence of this phenomenon in hereditary essential tremor is still debated. We describe a family in which three male members with essential tremor showed a progressive anticipation in onset age and an increased severity of clinical symptomatology
Anticipation of onset age in hereditary essential tremor / Bragoni, M; Fabbrini, Giovanni; DI LEGGE, S; Altieri, M; DI PIERO, Vittorio. - In: ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES. - ISSN 0392-0461. - STAMPA. - 18:(1997), pp. 45-47.
Anticipation of onset age in hereditary essential tremor
FABBRINI, Giovanni;DI PIERO, Vittorio
1997
Abstract
The genetic anticipation phenomenon has been described in several neurological disorders, often associated with unstable trinucleotide repeats in the affected genes. The occurrence of this phenomenon in hereditary essential tremor is still debated. We describe a family in which three male members with essential tremor showed a progressive anticipation in onset age and an increased severity of clinical symptomatologyI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
