This study shows that a short course of bortezomib may be effective in one-third of patients with symptomatic CAD failing previous treatments, with acceptable toxicity and longlasting benefit in the majority of responding patients. These data provide a rationale for further investigating the potential benefits of bortezomib either by using a more prolonged treatment schedule or in combination with other agents, particularly rituximab.
Short course of bortezomib in anemic patients with relapsed cold agglutinin disease: a phase 2 prospective GIMEMA study / Rossi, Giuseppe; Gramegna, Doriana; Paoloni, Francesca; Fattizzo, Bruno; Binda, Francesca; D’Adda, Mariella; Farina, Mirko; Lucchini, Elisa; Mauro, Francesca Romana; Salvi, Flavia; Marchetti, Monia; Fazi, Paola; Zaja and Wilma Barcellini, Francesco. - In: BLOOD. - ISSN 0006-4971. - ELETTRONICO. - 8:11(2018), pp. 547-550. [10.1182/blood-2018-03-835413]
Short course of bortezomib in anemic patients with relapsed cold agglutinin disease: a phase 2 prospective GIMEMA study
Francesca Romana MauroWriting – Review & Editing
;
2018
Abstract
This study shows that a short course of bortezomib may be effective in one-third of patients with symptomatic CAD failing previous treatments, with acceptable toxicity and longlasting benefit in the majority of responding patients. These data provide a rationale for further investigating the potential benefits of bortezomib either by using a more prolonged treatment schedule or in combination with other agents, particularly rituximab.| File | Dimensione | Formato | |
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