Purpose: Laryngopharyngeal reflux (LPR) is a frequent condition in Obstructive Sleep Apnoea (OSA) patients and different studies have been published in the last years about this topic. A review of the published literature regarding LPR in OSA patients has been reported. A meta-analysis to evaluate the incidence of LPR in OSA patients and correlate LPR positivity with OSA patients' characteristics has been performed. Methods: A comprehensive review of the English language literature about LPR in OSA patients was performed using the most important electronic databases (PubMed, EMBASE, the Cochrane Library etc.). A total of 10 papers studying LPR in OSA were assessed and considered eligible for the meta-analysis. Results: The data analysis regarding 870 identified OSA patients showed that 394 patients were LPR +, while 476 were LPR-. The meta-analysis showed no statistical difference regarding the AHI value between LPR + patients and LPR- patients (p = 0,3). Mean BMI was more higher in LPR + patients than in the patients without LPR, showing a significant statistical difference (p = 0.001). Conclusion: Current international literature demonstrates a high incidence of LPR (45.2%) in OSA patients. The severity of AHI in OSA patients would not seem to correlate with the presence of laryngopharyngeal reflux. The OSA patients with LPR showed a higher BMI compared with LPR- patients.

Laryngopharyngeal reflux in obstructive sleep apnoea patients: literature review and meta-analysis / Magliulo, Giuseppe; Iannella, Giannicola; Polimeni, Antonella; De Vincentiis, Marco; Meccariello, Giuseppe; Gulotta, Giampiero; Pasquariello, Benedetta; Montevecchi, Filippo; De Vito, Andrea; D'Agostino, Giovanni; Gobbi, Riccardo; Cammaroto, Giovanni; Vicini, Claudio. - In: AMERICAN JOURNAL OF OTOLARYNGOLOGY. - ISSN 0196-0709. - 39:6(2018), pp. 776-780. [10.1016/j.amjoto.2018.09.006]

Laryngopharyngeal reflux in obstructive sleep apnoea patients: literature review and meta-analysis

Magliulo, Giuseppe
Primo
;
Iannella, Giannicola
Secondo
;
Polimeni, Antonella;De Vincentiis, Marco;GULOTTA, GIAMPIERO;Pasquariello, Benedetta;
2018

Abstract

Purpose: Laryngopharyngeal reflux (LPR) is a frequent condition in Obstructive Sleep Apnoea (OSA) patients and different studies have been published in the last years about this topic. A review of the published literature regarding LPR in OSA patients has been reported. A meta-analysis to evaluate the incidence of LPR in OSA patients and correlate LPR positivity with OSA patients' characteristics has been performed. Methods: A comprehensive review of the English language literature about LPR in OSA patients was performed using the most important electronic databases (PubMed, EMBASE, the Cochrane Library etc.). A total of 10 papers studying LPR in OSA were assessed and considered eligible for the meta-analysis. Results: The data analysis regarding 870 identified OSA patients showed that 394 patients were LPR +, while 476 were LPR-. The meta-analysis showed no statistical difference regarding the AHI value between LPR + patients and LPR- patients (p = 0,3). Mean BMI was more higher in LPR + patients than in the patients without LPR, showing a significant statistical difference (p = 0.001). Conclusion: Current international literature demonstrates a high incidence of LPR (45.2%) in OSA patients. The severity of AHI in OSA patients would not seem to correlate with the presence of laryngopharyngeal reflux. The OSA patients with LPR showed a higher BMI compared with LPR- patients.
2018
laryngopharyngeal reflux; Obstructive Sleep Apnoea; OSA; reflux; otorhinolaryngology2734 pathology and forensic medicine
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Laryngopharyngeal reflux in obstructive sleep apnoea patients: literature review and meta-analysis / Magliulo, Giuseppe; Iannella, Giannicola; Polimeni, Antonella; De Vincentiis, Marco; Meccariello, Giuseppe; Gulotta, Giampiero; Pasquariello, Benedetta; Montevecchi, Filippo; De Vito, Andrea; D'Agostino, Giovanni; Gobbi, Riccardo; Cammaroto, Giovanni; Vicini, Claudio. - In: AMERICAN JOURNAL OF OTOLARYNGOLOGY. - ISSN 0196-0709. - 39:6(2018), pp. 776-780. [10.1016/j.amjoto.2018.09.006]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1148141
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