The treatment paradigm for thyroid cancer has shifted from a one-size-fits-all approach to more personalized protocols that range from active surveillance to total thyroidectomy followed by radioiodine remnant ablation. Accurate surveillance tools are available, but follow-up protocols vary widely between centres and clinicians, owing to the lack of clear, straightforward recommendations on the instruments and assessment schedule that health-care professionals should adopt. For most patients (that is, those who have had an excellent response to the initial treatment and have a low or intermediate risk of tumour recurrence), an infrequent assessment schedule is sufficient (such as a yearly determination of serum levels of TSH and thyroglobulin). Select patients will benefit from second-line imaging and more frequent assessments. This Review discusses the strengths and weaknesses of the surveillance tools and follow-up strategies that clinicians use as a function of the initial treatment and each patient’s risk of recurrence.

Follow-up of differentiated thyroid cancer – what should (and what should not) be done / Lamartina, Livia; Grani, Giorgio; Durante, Cosimo; Borget, Isabelle; Filetti, Sebastiano; Schlumberger, Martin. - In: NATURE REVIEWS. ENDOCRINOLOGY. - ISSN 1759-5029. - STAMPA. - 14:9(2018), pp. 538-551. [10.1038/s41574-018-0068-3]

Follow-up of differentiated thyroid cancer – what should (and what should not) be done

Lamartina, Livia
Primo
;
Grani, Giorgio
Secondo
;
Durante, Cosimo;Filetti, Sebastiano;SCHLUMBERGER, MARTIN
Ultimo
2018

Abstract

The treatment paradigm for thyroid cancer has shifted from a one-size-fits-all approach to more personalized protocols that range from active surveillance to total thyroidectomy followed by radioiodine remnant ablation. Accurate surveillance tools are available, but follow-up protocols vary widely between centres and clinicians, owing to the lack of clear, straightforward recommendations on the instruments and assessment schedule that health-care professionals should adopt. For most patients (that is, those who have had an excellent response to the initial treatment and have a low or intermediate risk of tumour recurrence), an infrequent assessment schedule is sufficient (such as a yearly determination of serum levels of TSH and thyroglobulin). Select patients will benefit from second-line imaging and more frequent assessments. This Review discusses the strengths and weaknesses of the surveillance tools and follow-up strategies that clinicians use as a function of the initial treatment and each patient’s risk of recurrence.
2018
Endocrinology, Diabetes and Metabolism; Endocrinology
01 Pubblicazione su rivista::01a Articolo in rivista
Follow-up of differentiated thyroid cancer – what should (and what should not) be done / Lamartina, Livia; Grani, Giorgio; Durante, Cosimo; Borget, Isabelle; Filetti, Sebastiano; Schlumberger, Martin. - In: NATURE REVIEWS. ENDOCRINOLOGY. - ISSN 1759-5029. - STAMPA. - 14:9(2018), pp. 538-551. [10.1038/s41574-018-0068-3]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1138927
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