Background: Obstructive sleep apnea syndrome and is characterized by recurrent episodes of partial or complete upper airway collapse during sleep with consequent oxygen desaturations and cardiovascular, neurological, and metabolic impairment. Clinical presentation: The authors report the case of a 66-year-old male presenting “metabolic syndrome” (obesity, impaired glucose tolerance, dyslipidemia, multi-drug treated arterial hypertension), atopy, mouth breathing due to turbinate hypertrophy, and pathological daytime sleepiness. As patient’s compliance to standard continuous positive airway pressure (CPAP) therapy was poor, he was treated using low-pressure CPAP combined with a mandibular advancement device (MAD). Conclusion: In selected patients, a treatment combining CPAP and MAD might be a more tolerable alternative to CPAP alone. The improved pharyngeal patency, promoted by mandibular advancement and stretching of the pharyngeal muscles, allows operating the CPAP at lower pressures when the MAD alone is not sufficient to induce a safe sleep profile.

Difficult-to-treat OSAS: combined continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) therapy. A case report / Luzzi, Valeria; Brunori, Marco; Terranova, Sergio; DI PAOLO, Carlo; Ierardo, Gaetano; Vozza, Iole; Polimeni, Antonella. - In: CRANIO. - ISSN 0886-9634. - ELETTRONICO. - 38:3(2020), pp. 196-200. [10.1080/08869634.2018.1496628]

Difficult-to-treat OSAS: combined continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) therapy. A case report

Luzzi, Valeria
Primo
;
Brunori, Marco
Secondo
;
DI PAOLO, Carlo;Ierardo, Gaetano;VOZZA, Iole
Penultimo
;
Polimeni, Antonella
Ultimo
2020

Abstract

Background: Obstructive sleep apnea syndrome and is characterized by recurrent episodes of partial or complete upper airway collapse during sleep with consequent oxygen desaturations and cardiovascular, neurological, and metabolic impairment. Clinical presentation: The authors report the case of a 66-year-old male presenting “metabolic syndrome” (obesity, impaired glucose tolerance, dyslipidemia, multi-drug treated arterial hypertension), atopy, mouth breathing due to turbinate hypertrophy, and pathological daytime sleepiness. As patient’s compliance to standard continuous positive airway pressure (CPAP) therapy was poor, he was treated using low-pressure CPAP combined with a mandibular advancement device (MAD). Conclusion: In selected patients, a treatment combining CPAP and MAD might be a more tolerable alternative to CPAP alone. The improved pharyngeal patency, promoted by mandibular advancement and stretching of the pharyngeal muscles, allows operating the CPAP at lower pressures when the MAD alone is not sufficient to induce a safe sleep profile.
2020
obstructive sleep apnea; airway pressure; mandibular advancement
01 Pubblicazione su rivista::01a Articolo in rivista
Difficult-to-treat OSAS: combined continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) therapy. A case report / Luzzi, Valeria; Brunori, Marco; Terranova, Sergio; DI PAOLO, Carlo; Ierardo, Gaetano; Vozza, Iole; Polimeni, Antonella. - In: CRANIO. - ISSN 0886-9634. - ELETTRONICO. - 38:3(2020), pp. 196-200. [10.1080/08869634.2018.1496628]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1132409
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