ABSTRACT Hepatocyte transplantation has been used for temporary metabolic support of patients in end-stage liver failure awaiting whole organ transplantation as a method to support liver function and facilitate regeneration of the native liver in cases of fulminant hepatic failure and as a “cellular therapy” for patients with genetic defects in vital liver functions. The aim of this paper was to discuss the basic research that led to clinical hepatocyte transplanta- tion, the published clinical experience with this experimental technique, and some possible future uses of hepatocyte transplantation.
HISTORICAL ASPECTS OF HEPATOCYTE TRANSPLANTATION / Bruzzone, Paolo; S. C., Strom. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 38:4(2006), pp. 1179-1180. [10.1016/j.transproceed.2006.02.138]
HISTORICAL ASPECTS OF HEPATOCYTE TRANSPLANTATION
BRUZZONE, Paolo;
2006
Abstract
ABSTRACT Hepatocyte transplantation has been used for temporary metabolic support of patients in end-stage liver failure awaiting whole organ transplantation as a method to support liver function and facilitate regeneration of the native liver in cases of fulminant hepatic failure and as a “cellular therapy” for patients with genetic defects in vital liver functions. The aim of this paper was to discuss the basic research that led to clinical hepatocyte transplanta- tion, the published clinical experience with this experimental technique, and some possible future uses of hepatocyte transplantation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
