2-deoxy-5-fluorouridine, also known as floxuridine (FUdr) is a fluoropyridine antimetabolite, used in the treatment of metastatic renal cell carcinoma. We report the first case of lesional pulmonary oedema developed after receiving Fudr, recently treated in our unit. The patient refused endotracheal intubation, and was successfully treated associating noninvasive ventilation (NIV) with full-face mask to steroid treatment. The authors conclude that mechanical ventilation via face-mask can be an effective, comfortable, dignified method of support for patients with end-stage disease and acute respiratory failure.

Non invasive ventilation in the trearment of FUdr-induced lesional Ppulmonary oedema / Conti, G; Spadetta, Gustavo; Rocco, Monica; Antonelli, M; Ruscio, L; Gionfrida, E; Angiuli, G.. - In: MINERVA ANESTESIOLOGICA. - ISSN 0375-9393. - 66:7-8(2000), pp. 561-564.

Non invasive ventilation in the trearment of FUdr-induced lesional Ppulmonary oedema

SPADETTA, Gustavo;ROCCO, Monica;
2000

Abstract

2-deoxy-5-fluorouridine, also known as floxuridine (FUdr) is a fluoropyridine antimetabolite, used in the treatment of metastatic renal cell carcinoma. We report the first case of lesional pulmonary oedema developed after receiving Fudr, recently treated in our unit. The patient refused endotracheal intubation, and was successfully treated associating noninvasive ventilation (NIV) with full-face mask to steroid treatment. The authors conclude that mechanical ventilation via face-mask can be an effective, comfortable, dignified method of support for patients with end-stage disease and acute respiratory failure.
2000
pulmonary edema; non invasive ventilation; floxuridine
01 Pubblicazione su rivista::01a Articolo in rivista
Non invasive ventilation in the trearment of FUdr-induced lesional Ppulmonary oedema / Conti, G; Spadetta, Gustavo; Rocco, Monica; Antonelli, M; Ruscio, L; Gionfrida, E; Angiuli, G.. - In: MINERVA ANESTESIOLOGICA. - ISSN 0375-9393. - 66:7-8(2000), pp. 561-564.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/112955
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