Kinase inhibitors (KIs) are a class of anticancer drugs that inhibit activity of the enzymes protein kinases, which regulate crucial cellular processes and have a demonstrated role in human oncogenesis. Treatment of advanced forms of endocrine cancer which are not responsive to cytotoxic chemotherapies is challenging and use of KIs is gaining a growing role in this field.

Targeted therapy with kinase inhibitors in aggressive endocrine tumors / Marotta, Vincenzo; Franzese, Maria Domenica; Del Prete, Michela; Chiofalo, Maria Grazia; Ramundo, Valeria; Esposito, Raffaella; Marciello, Francesca; Pezzullo, Luciano; Carratù, Annachiara; Vitale, Mario; Colao, Annamaria; Faggiano, Antongiulio. - In: EXPERT OPINION ON PHARMACOTHERAPY. - ISSN 1744-7666. - 14:9(2013), pp. 1187-1203. [10.1517/14656566.2013.796931]

Targeted therapy with kinase inhibitors in aggressive endocrine tumors

Ramundo, Valeria;Faggiano, Antongiulio
2013

Abstract

Kinase inhibitors (KIs) are a class of anticancer drugs that inhibit activity of the enzymes protein kinases, which regulate crucial cellular processes and have a demonstrated role in human oncogenesis. Treatment of advanced forms of endocrine cancer which are not responsive to cytotoxic chemotherapies is challenging and use of KIs is gaining a growing role in this field.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/1120849
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