We read with great interest the comment letter by Winter et al. on our recently published study on the new concept of intention-to-treat (ITT) survival benefit of liver transplantation (LT) in patients with hepatocellular cancer (HCC).(1)Winter et al. reported some comments mainly focused on the methodological approach used for constructing the mathematical model. We draw attention to the supplementary section of our article in which we explain our approach. We did not mean to imply that the construction of our benefit model was innovative. Nor did we ignore the seminal works of Merion and Schaubel, which we referred to in our article. Rather, the innovation of our work is connected with its ITT design.
Reply / Lai, Quirino; Vitale, Alessandro. - In: HEPATOLOGY. - ISSN 0270-9139. - ELETTRONICO. - 67:4(2018), pp. 1639-1640. [10.1002/hep.29757]
Reply
Lai, Quirino;
2018
Abstract
We read with great interest the comment letter by Winter et al. on our recently published study on the new concept of intention-to-treat (ITT) survival benefit of liver transplantation (LT) in patients with hepatocellular cancer (HCC).(1)Winter et al. reported some comments mainly focused on the methodological approach used for constructing the mathematical model. We draw attention to the supplementary section of our article in which we explain our approach. We did not mean to imply that the construction of our benefit model was innovative. Nor did we ignore the seminal works of Merion and Schaubel, which we referred to in our article. Rather, the innovation of our work is connected with its ITT design.| File | Dimensione | Formato | |
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