USE OF AUTOLOGOUS PLATELET GEL FOR RECURRENCE OF PERINEAL AND SACROCOCCIGEAL FISTULA

USE OF AUTOLOGOUS PLATELET GEL FOR RECURRENCE OF PERIANAL AND SACRO-COCCIGEAL FISTULA A. Giuliani, G. Ferrazza, D. Crocetti, L. de Anna, E. Orsi, F. Guerra, F. La Torre Coloproctology Unit, Department of Emergency, Policlinico Umberto I, University of ‘‘La Sapienza’’, Rome, Italy Abstract The treatment of Sinus Pilonidalis and Perianal Fistulas is still not entirely standardised due to the frequency of relapses, the inconvenience for patients and last but not least, for the economic commitment by the health-care structure. The potential therapeutic value and versatility of products stemming from blood and platelets have long stimulated research and interest in the field of surgery. The autologous gel platelets (PG), generated by activated human thrombin and platelets, represent a new biotechnology for angiogenesis stimulation on speeding up the healing and regeneration of tissues. Do not underestimate its effect as analgesic. Our study shows the employment of gel platelets in the treatment of complicated wounds and recurrences following surgery for Sinus Pilonidalis and Perianal Fistulas . From January 2006 to May 2009, we selected eight patients (6 males and 2 females, aged between 19 and 54 years) with infected wound following surgery for Sinus Pilonidalis and 10 patients (6 males and 4 females, aged between 31 and 72 years) with recurrence after Perianal Fistulas Our results, although obtained on a small group of patients, support the safety and efficacy of PG in the treatment of infected wounds following surgery for the excision of Sinus Pilonidalis and Perianal Fistulas relapses. Further studies and longer follow-up are needed to come to any conclusion.