In this work, the design and fabrication of a miniaturized and light-weight biosensor that can be used to monitor the biological effects of hostile ultraviolet radiation in earth and space are presented. The biosensor is generated by embedding a sensitive element to UV radiation, DNA, in a hybrid carbon-based nanomaterial. In particular, we present results on the fabrication and characterization of hybrid nanostructured films containing graphene nanoplatelets (GNPs) and double-stranded DNA for the in situ and real-time detection of UV radiation damaging effects from the changes of the film electrical properties induced by exposure to UV-C radiation. The biosensor is realized by the deposition of the sensitive unit GNP/DNA on a supporting substrate made of flexible polymers or glass.

Nanomaterial-based biosensors for a real-time detection of biological damage by UV light / Santonicola, Mariagabriella; Coscia, Marta Gina; Sirilli, Matteo; Laurenzi, Susanna. - ELETTRONICO. - 2015-November:(2015), pp. 4391-4394. ((Intervento presentato al convegno 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 tenutosi a Milan, Italy [10.1109/EMBC.2015.7319368].

Nanomaterial-based biosensors for a real-time detection of biological damage by UV light

Santonicola, Mariagabriella
;
Coscia, Marta Gina;Laurenzi, Susanna
2015

Abstract

In this work, the design and fabrication of a miniaturized and light-weight biosensor that can be used to monitor the biological effects of hostile ultraviolet radiation in earth and space are presented. The biosensor is generated by embedding a sensitive element to UV radiation, DNA, in a hybrid carbon-based nanomaterial. In particular, we present results on the fabrication and characterization of hybrid nanostructured films containing graphene nanoplatelets (GNPs) and double-stranded DNA for the in situ and real-time detection of UV radiation damaging effects from the changes of the film electrical properties induced by exposure to UV-C radiation. The biosensor is realized by the deposition of the sensitive unit GNP/DNA on a supporting substrate made of flexible polymers or glass.
37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Biosensing Techniques; DNA; Graphite; Ultraviolet Rays; Nanostructures
04 Pubblicazione in atti di convegno::04b Atto di convegno in volume
Nanomaterial-based biosensors for a real-time detection of biological damage by UV light / Santonicola, Mariagabriella; Coscia, Marta Gina; Sirilli, Matteo; Laurenzi, Susanna. - ELETTRONICO. - 2015-November:(2015), pp. 4391-4394. ((Intervento presentato al convegno 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 tenutosi a Milan, Italy [10.1109/EMBC.2015.7319368].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1116517
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