The retinoic acid (RA) is a vitamin A metabolite that, in the mouse, has been demonstrated to regulate the spermatogonial differentiation, the meiotic entry, the initiation of the spermatid elongation and the release of spermatozoa. Over the years several RA responsive genes have been identified. They have been involved in the mediation of one or more events. Among others Stra8 is crucial to induce the spermatogonial differentiation and the meiotic entry [1]. In our study we tested the hypothesis that the RA is able to regulate the same genes in the human spermatogonia.
Retinoic acid regulation of human spermatogonial genes / DI PERSIO, Sara; Saracino, Rossana; Fera, Stefania; Vicini, Elena. - (2018). (Intervento presentato al convegno 20th European Testis Workshop tenutosi a Obidos, Portogallo).
Retinoic acid regulation of human spermatogonial genes
Di Persio Sara;Saracino Rossana;Fera Stefania;Vicini Elena
2018
Abstract
The retinoic acid (RA) is a vitamin A metabolite that, in the mouse, has been demonstrated to regulate the spermatogonial differentiation, the meiotic entry, the initiation of the spermatid elongation and the release of spermatozoa. Over the years several RA responsive genes have been identified. They have been involved in the mediation of one or more events. Among others Stra8 is crucial to induce the spermatogonial differentiation and the meiotic entry [1]. In our study we tested the hypothesis that the RA is able to regulate the same genes in the human spermatogonia.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
