This study hereby reports the case of a 19-year old boy with a gamma-delta hepatosplenic T-cell lymphoma (HSTCL). Initial therapy consisted of four cycles of the IEV (Ifosphamide, Epirubicin and Etoposide) scheme. Further treatment strategy was then adapted according to minimal residual disease monitoring by immunophenotypic and T-cell receptor gamma chain gene evaluation. The patient remains in complete clinical, immunological and molecular remission and in good clinical conditions 48 months after diagnosis and 40 months after stopping therapy.

Gamma-delta hepatosplenic T-cell lymphoma. Description of a case with immunophenotypic and molecular follow-up succesfully treated with chemotherapy alone / Moleti, Ml; Testi, A.; Giona, F; Amendola, A; Palumbo, G; Uccini, S; Starza, Id; DE PROPRIS MS, ; Guarini, A; Foa, R. - In: LEUKEMIA & LYMPHOMA. - ISSN 1042-8194. - 47:2(2006), pp. 333-336. [10.1080/10428190500293321]

Gamma-delta hepatosplenic T-cell lymphoma. Description of a case with immunophenotypic and molecular follow-up succesfully treated with chemotherapy alone

MOLETI ML;A. TESTI;GIONA F;AMENDOLA A;PALUMBO G;UCCINI S;GUARINI A;FOA R
2006

Abstract

This study hereby reports the case of a 19-year old boy with a gamma-delta hepatosplenic T-cell lymphoma (HSTCL). Initial therapy consisted of four cycles of the IEV (Ifosphamide, Epirubicin and Etoposide) scheme. Further treatment strategy was then adapted according to minimal residual disease monitoring by immunophenotypic and T-cell receptor gamma chain gene evaluation. The patient remains in complete clinical, immunological and molecular remission and in good clinical conditions 48 months after diagnosis and 40 months after stopping therapy.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/110688
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