Acetylsalicylic acid (ASA, Aspirin) is among the most used drugs worldwide. At present, Aspirin represents a quite versatile drug employed in the control of pain symptomatologies and in situations such as prevention of both ischaemic stroke and cardiovascular events. Aspirin causes inhibition of prostaglandin (PG) synthesis by inactivation of the cyclooxygenase (COX) enzyme. ASA constitutes the focus of new researches explaining more widely Aspirin's control of inflammation. The induction of the endogenous epimers lipoxins (Aspirin-triggered15-epi-lipoxins, ATLs) represents one of the most recent achievements. This particular feature of Aspirin is not shared by other NSAIDs. ASA is well known as a headache medication, figuring as apossible treatment choice in tension-type headache but also in acute migraine attacks. Furthermore, a new Aspirin formulation with a greater rapidity of action has been introduced. In conclusion, little information exists on the subject and more studies are required. © Springer-Verlag Italia 2007.

Aspirin and tension-type headache / I., Farinelli; Martelletti, Paolo. - In: THE JOURNAL OF HEADACHE AND PAIN. - ISSN 1129-2369. - 8:1(2007), pp. 49-55. [10.1007/s10194-006-0357-4]

Aspirin and tension-type headache

MARTELLETTI, Paolo
2007

Abstract

Acetylsalicylic acid (ASA, Aspirin) is among the most used drugs worldwide. At present, Aspirin represents a quite versatile drug employed in the control of pain symptomatologies and in situations such as prevention of both ischaemic stroke and cardiovascular events. Aspirin causes inhibition of prostaglandin (PG) synthesis by inactivation of the cyclooxygenase (COX) enzyme. ASA constitutes the focus of new researches explaining more widely Aspirin's control of inflammation. The induction of the endogenous epimers lipoxins (Aspirin-triggered15-epi-lipoxins, ATLs) represents one of the most recent achievements. This particular feature of Aspirin is not shared by other NSAIDs. ASA is well known as a headache medication, figuring as apossible treatment choice in tension-type headache but also in acute migraine attacks. Furthermore, a new Aspirin formulation with a greater rapidity of action has been introduced. In conclusion, little information exists on the subject and more studies are required. © Springer-Verlag Italia 2007.
2007
acute treatment; asa; aspirin; tension-type headache
01 Pubblicazione su rivista::01a Articolo in rivista
Aspirin and tension-type headache / I., Farinelli; Martelletti, Paolo. - In: THE JOURNAL OF HEADACHE AND PAIN. - ISSN 1129-2369. - 8:1(2007), pp. 49-55. [10.1007/s10194-006-0357-4]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/110651
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