Bone involvements in chronic lymphocytic leukemia (CLL) are considered rare events, and the English-language medical literature describes them only in sporadic case reports. Consequently, robust indications for a rational clinical management are lacking. We report the case of a middle-aged man in clinical follow-up for CLL who experienced pain at the right tibial level that was refractory to nonsteroidal anti-inflammatory drugs and an acute episode of anemia. Instrumental examinations and a bioptic sample surprisingly demonstrated a bone tibial localization by CLL.
A rare case of appendicular skeleton localization in a patient with chronic lymphocytic leukemia successfully treated with salvage radiation therapy / Tuscano, Carmelo; Vincelli, Iolanda Donatella; Arico, Demetrio; Marchione, Anna Maria; Versace, Paolo; Stelitano, Caterina; Porta, Natale; Petrozza, Vincenzo; Di Cristofano, Claudio; Sceni, Giuseppe; Ronco, Francesca; Russi, Elvio Grazioso; Al Sayyad, Said. - In: ADVANCES IN RADIATION ONCOLOGY. - ISSN 2452-1094. - STAMPA. - 3:2(2017), pp. 121-124. [10.1016/j.adro.2017.01.007]
A rare case of appendicular skeleton localization in a patient with chronic lymphocytic leukemia successfully treated with salvage radiation therapy
Porta, Natale;Petrozza, Vincenzo;Di Cristofano, Claudio;
2017
Abstract
Bone involvements in chronic lymphocytic leukemia (CLL) are considered rare events, and the English-language medical literature describes them only in sporadic case reports. Consequently, robust indications for a rational clinical management are lacking. We report the case of a middle-aged man in clinical follow-up for CLL who experienced pain at the right tibial level that was refractory to nonsteroidal anti-inflammatory drugs and an acute episode of anemia. Instrumental examinations and a bioptic sample surprisingly demonstrated a bone tibial localization by CLL.File | Dimensione | Formato | |
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