Cholestasis is frequently encountered in human liver transplants. In a series of 82 liver fine-needle aspiration biopsies performed in 20 grafted patients, the incidence rate of cholestasis was 55%. Cholestasis may predominantly be localized in the hepatocyte cytoplasm, or in the biliary tree or in both sites. In our cases it was most frequently associated with acute rejection (53%), followed by preservation injuries (29%) and ciclosporin toxicity (12%), respectively. The severity and the chronologic distribution of cholestatic episodes seem to vary according to the other associated pathologic conditions.
CHOLESTASIS IN LIVER TRANSPLANTATION: INCIDENCE AND DIAGNOSTIC SIGNIFICANCE / Pecorella, Irene; Ciardi, Antonio; Rahimi, S; DI TONDO, U.. - In: PATHOLOGICA. - ISSN 0031-2983. - STAMPA. - 82:(1990), pp. 513-518.
CHOLESTASIS IN LIVER TRANSPLANTATION: INCIDENCE AND DIAGNOSTIC SIGNIFICANCE
PECORELLA, Irene;CIARDI, Antonio;
1990
Abstract
Cholestasis is frequently encountered in human liver transplants. In a series of 82 liver fine-needle aspiration biopsies performed in 20 grafted patients, the incidence rate of cholestasis was 55%. Cholestasis may predominantly be localized in the hepatocyte cytoplasm, or in the biliary tree or in both sites. In our cases it was most frequently associated with acute rejection (53%), followed by preservation injuries (29%) and ciclosporin toxicity (12%), respectively. The severity and the chronologic distribution of cholestatic episodes seem to vary according to the other associated pathologic conditions.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
