The adhesiveness of a mucous strain of Pseudomonas aeruginosa to rabbit bladder mucosa has been investigated after pretreatment of the vesical mucosa with different glycosidases. Using a simple apparatus the study was carried out in parallel on samples of untreated and pre-treated mucosa. The results obtained showed that the cleavage of terminal sugar by addition of neuraminidase, N-acetyl-beta-D-glucosaminidase, alpha-mannosidase, alpha-L-fucosidase and beta-galactosidase produced a decrease in the number of adhered bacteria. A more drastic enzymatic action due to the combined effect of neuraminidase + alpha-L-fucosidase and neuraminidase + beta-galactosidase produced, on the other hand, an increased adhesion of bacteria, probably due to an unmasking of new receptor sites.

Adhesiveness of Pseudomonas aeruginosa to rabbit vesical mucosa effect of glycosidases on cellular binding / Chiarini, Fernanda; Mastromarino, Paola; Orsi, Giovanni Battista; T., Riscaldati. - In: ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITÀ. - ISSN 1120-9135. - STAMPA. - 1:1-2(1989), pp. 399-408.

Adhesiveness of Pseudomonas aeruginosa to rabbit vesical mucosa effect of glycosidases on cellular binding.

CHIARINI, Fernanda;MASTROMARINO, Paola;ORSI, Giovanni Battista;
1989

Abstract

The adhesiveness of a mucous strain of Pseudomonas aeruginosa to rabbit bladder mucosa has been investigated after pretreatment of the vesical mucosa with different glycosidases. Using a simple apparatus the study was carried out in parallel on samples of untreated and pre-treated mucosa. The results obtained showed that the cleavage of terminal sugar by addition of neuraminidase, N-acetyl-beta-D-glucosaminidase, alpha-mannosidase, alpha-L-fucosidase and beta-galactosidase produced a decrease in the number of adhered bacteria. A more drastic enzymatic action due to the combined effect of neuraminidase + alpha-L-fucosidase and neuraminidase + beta-galactosidase produced, on the other hand, an increased adhesion of bacteria, probably due to an unmasking of new receptor sites.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/109455
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